Results 261 to 270 of about 11,905,956 (387)

Protocol to measure human IL-6 secretion from CAR T cell-primed macrophage and monocyte lineage cells in vitro and in vivo using humanized mice

STAR Protocols
Summary: Chimeric antigen receptor (CAR) T cell therapy often causes serious toxicities, such as cytokine release syndrome (CRS), mainly due to interleukin-6 (IL-6) secreted by monocyte lineage cells.
Thao Nguyen, Toshiaki Yoshikawa, Yusuke Ito, Hitomi Kasuya, Takahiro Nakashima, Sachiko Okamoto, Yasunori Amaishi, Haosong Zhang, Yang Li, Tetsuya Matsukawa, Satoshi Inoue, Yuki Kagoya   +11 more
doaj  

Agent-based modeling for personalized prediction of an experimental immune response to immunotherapeutic antibodies. [PDF]

PLoS One
Matalon O, Perissinotto A, Baruch K, Braiman S, Geiger Maor A, Yoles E, Wilczynski E, Nevo U, Priel A.   +8 more
europepmc   +1 more source

Co‐expression of HSV‐1 ICP34.5 enhances the expression of gene delivered by self‐amplifying RNA and mitigates its immunogenicity

FEBS Open Bio, EarlyView.
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu, Yabin Wu, Chunye Zhao, Jie Zheng, Shangwu Chen, Yigang Wang, Yulong Xia   +6 more
wiley   +1 more source

Recognition of microorganisms and activation of the immune response

Nature, 2007
R. Medzhitov
semanticscholar   +1 more source

Immune Response to Bioluminescence Imaging Reporters in Murine Tumor Models. [PDF]

Mol Imaging Biol
Basnet A, Thomas DD, Landreth KM, Damron FH, Liu TW.   +4 more
europepmc   +1 more source

THE IMMUNE RESPONSE OF RABBITS TOLERANT TO BOVINE SERUM ALBUMIN TO THE INJECTION OF OTHER HETEROLOGOUS SERUM ALBUMINS [PDF]

, 1961
William O. Weigle
openalex   +1 more source

Comparative study of adenosine 3′‐pyrophosphokinase domains of MuF polymorphic toxins

FEBS Open Bio, EarlyView.
With the ultimate goal of understanding the association of toxin‐immunity modules to temperate phages, we characterized toxins from three prophages and examined cross‐protection from immunity proteins. The toxins exhibit adenosine 3′‐pyrophosphokinase activity and are toxic in Escherichia coli.
Eloïse M. Paulet, Julia Bartoli, Atakan Kabtan, Chloé M. Piras, Audrey C. Tempier, Eric Cascales, Julie P. Viala   +6 more
wiley   +1 more source

MYC regulates the antitumor immune response through CD47 and PD-L1

Science, 2016
S. Casey, Ling Tong, Yulin Li, R. Do, S. Walz, Kelly N Fitzgerald, A. Gouw, Virginie Baylot, I. Gütgemann, M. Eilers, D. Felsher   +10 more
semanticscholar   +1 more source

Neutralizing Antibodies: Role in Immune Response and Viral Vector Based Gene Therapy. [PDF]

Int J Mol Sci
Tsaregorodtseva TS, Gubaidullina AA, Kayumova BR, Shaimardanova AA, Issa SS, Solovyeva VV, Sufianov AA, Sufianova GZ, Rizvanov AA.   +8 more
europepmc   +1 more source

A Role of Macrophages in the Stimulation of Immune Responses by Adjuvants [PDF]

, 1969
Emil R. Unanue, Brigitte A. Askonas, A. C. Allison   +2 more
openalex   +1 more source