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Complement and the immune response

Current Opinion in Immunology, 1997
This past year has seen a major advance in our understanding of how the complement system enhances the adaptive immune response. The use of in vivo models has revealed that direct coupling of C3d to antigen is sufficient to dramatically reduce the amount of antigen required for a secondary response.
Michael C. Carroll, Michael B. Fischer
openaire   +3 more sources

Prostaglandins and the immune response

Life Sciences, 1977
Abstract The experimental evidence amply demonstrates that exogenous Pg is capable of inhibiting most immunological functions. The physiological role of Pgs in immune cell regulation, however, remains unresolved. This uncertainty arises from the fact that although Pgs are normally found in tissues in nanogram quantities or less, many experiments ...
Helen R. Strausser, Louis M. Pelus
openaire   +3 more sources

Tryptophan and the immune response

Immunology & Cell Biology, 2003
The immune system continuously modulates the balance between responsiveness to pathogens and tolerance to non‐harmful antigens. The mechanisms that mediate tolerance are not well understood, but recent findings have implicated tryptophan catabolism through the kynurenine metabolic pathway as one of many mechanisms involved.
John R. Moffett, M. A. Aryan Namboodiri
openaire   +3 more sources

Maturation of the Immune Response

1996
This chapter focuses on the maturation of the immune response. The maturation of the immune system is considered to be a precisely controlled process, which results in a large number of highly differentiated cells, each committed to the production of a single (antibody).
Michael S. Neuberger, Cesar Milstein
openaire   +3 more sources

Dermatophytosis and the immune response

Journal of the American Academy of Dermatology, 1994
Dermatophytes are eliminated from the skin by a cell-mediated immune reaction. Immunity is acquired by active infection. The inflammatory reaction that ensues may increase the proliferatory activity of keratinocytes, causing the fungus to be sloughed from the skin surface.
openaire   +3 more sources

Development of the immune response

Clinical & Experimental Allergy, 1973
SummaryThe association of immunodeficiency with allergy is increasingly recognized. It is likely that defective antigen handling as a consequence of subtle degrees of immunodeficiency could predispose an individual to clinical allergy. Patterns of antigen handling established at first contact after birth with an antigen may affect the course of immune ...
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Environmental pollutants and the immune response

Nature Immunology, 2020
Takafumi Suzuki   +3 more
semanticscholar   +1 more source

PD-L1 as a biomarker of response to immune-checkpoint inhibitors

Nature Reviews Clinical Oncology, 2021
D. Doroshow   +9 more
semanticscholar   +1 more source

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