Results 211 to 220 of about 2,089,667 (358)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Associations between gut microbiota and immune status in untreated B-cell lymphoma patients. [PDF]

Front Immunol
Zhou J, Yao J, Hu N, Su J.
europepmc   +1 more source

EFFECT OF DIETARY BANANA PSEUDO-STEM SIMPLICIA, COMMERCIAL VACCINE, AND THEIR COMBINATION ON THE GROWTH, HEALTH STATUS, AND IMMUNITY PERFORMANCE OF NILE TILAPIA AGAINST Aeromonas hydrophila

Dinamella Wahjuningrum, Erina Tri Ramadhina, Sri Nuryati, Ita Rizkiyanti, Taufiq Abdullah   +4 more
openalex   +1 more source

Effect of immunity inductors on the structural and functional state of photosynthetic apparatus and oxidative status of cucumber plants (cucumis sativus l.) Infected by Fusarium oxysporum

, 2019
Л. М. Абрамчик, I. N. Domanskaya, В. Н. Макаров, Е. В. Сердюченко, T. S. Bachyshcha, V.V. Kondratieva, S. N. Shpilevski, Yu. N. Daubniuk, Luidmila F. Kabashnikova   +8 more
openalex   +2 more sources

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

The efferocytosis-related genes of SLC26A6, TYRO3, and PDK4 have been identified as predictors of prognosis in hepatocellular carcinoma and are associated with the immune status. [PDF]

Int J Med Sci
Yang JJ, Ouyang Q, Zeng XX, Cen WJ, Deng L, Song GP, Wang F, Sun LY.   +7 more
europepmc   +1 more source

Functional activity of blood neutrophils and immune status of heifers under the influence of probiotics

Svetoslav Farafonov, Olha Yaremko, B. V. Gutyj, Nikolay Cherniy, V. S. Kozyr, Anna Lykhach, Pavlo Skliarov, Olena Khmeleva, Daria Mylostуva, Roman Mylostyvyi   +9 more
openalex   +2 more sources

Parameters of homocystein and features of the immune status in persons working in the chemical industry

, 2006
Т. Т. Радзивил, I. V. Krat, I. V. Oradovskaya   +2 more
openalex   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Monitoring mitochondrial function in peripheral T cells to assess immune status and graft health after kidney transplantation. [PDF]

Front Immunol
Zhang E, Wan Z, Ma Y, Li Y, Zhou Q, Cai B, Li Y, Li F, Ying B, Yan L.   +9 more
europepmc   +1 more source