Results 111 to 120 of about 2,378,169 (247)

ИММУНОЛОГИЧЕСКИЕ И МОРФОФУНКЦИОНАЛЬНЫЕ ИЗМЕНЕНИЯ ЛЕЙКОЦИТОВ ПРИ ИСПОЛЬЗОВАНИИ МИКРОБИАЛЬНОГО ИММУНОСТИМУЛЯТОРА У КОРОВ

Ветеринарная патология, 2012
The article describes the effect of microbially-derived experimental immune stimulant on quantity and morphofunctional properties of peripheral blood leucocytes in cows.

doaj  

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Integrated multi-omics analysis reveals shared IFN-γ-associated monocyte signatures in primary Sjögren’s syndrome and Alzheimer’s disease

Frontiers in Immunology
BackgroundPrimary Sjögren’s syndrome (pSS) is epidemiologically associated with an increased risk of Alzheimer’s disease (AD); however, the shared IFN-γ-related immune mechanisms underlying this association remain poorly understood.MethodsPeripheral ...
Xiaohan Zhang, Shaofu Yan, Minghui Xu, Yanxin Zhang, Wenqi Tan, Tingjun Li, Jinyan Si, Jinyan Si, Ping Sun   +8 more
doaj   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

The effect of HIV-exposure on immune responses to expanded programme on immunization vaccines and antigens [PDF]

, 2013
Includes abstract.Includes bibliographical references.Immunization against vaccine-preventable infections is essential to reducing childhood morbidity and mortality.
Kidzeru, Elvis Banboye
core   +1 more source

Functional analysis of TL1A/DR3 interactions during T cell-mediated immune responses

Members of the tumour necrosis factor superfamily (TNFSF) are important regulators of inflammation and immunity. TL1A (TNFSF15), ligand for death receptor 3 (DR3), is the most recently discovered member of this superfamily and full understanding of its ...
Ślebioda, Tomasz Jerzy
core   +1 more source

Controlled progressive innate immune stimulation regimen prevents the induction of sickness behavior in the open field test

Journal of Inflammation Research, 2013
Qun Chen, Andrew J Tarr, Xiaoyu Liu, Yufen Wang, Nathaniel S Reed, Cameron P DeMarsh, John F Sheridan, Ning QuanDivision of Oral Biology, Institute for Behavioral Medicine Research, The Ohio State University, Columbus, OH, USAAbstract: Peripheral immune ...
Chen Q, Tarr AJ, Liu X, Wang Y, Reed NS, DeMarsh CP, Sheridan JF, Quan N   +7 more
doaj  

Long-term music stimulating alleviated the inflammatory responses caused by acute noise stress on the immune organs of broilers by NF-κB signaling pathway

Ecotoxicology and Environmental Safety
As an environmental enrichment, music can positively influence the immune function, while noise has an adverse effect on the physical and mental health of humans and animals.
Haowen Wang, Yiwen Chai, Yandong Xu, Yulai Wang, Jianhong Li, Runxiang Zhang, Jun Bao   +6 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source