Results 171 to 180 of about 3,483,015 (354)

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Associating Changes in the Immune System with Clinical Diseases for Interpretation in Risk Assessment [PDF]

open access: bronze, 2004
Michael I. Luster   +5 more
openalex   +1 more source

Time, the final frontier

open access: yesMolecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain   +3 more
wiley   +1 more source

The vitamin D receptor and the etiology of RANTES/CCL-expressive fatty-degenerative osteolysis of the jawbone: an interface between osteoimmunology and bone metabolism

open access: yesInternational Journal of General Medicine, 2018
Johann Lechner,1 Jürgen Aschoff,2 Tatjana Rudi3 1Clinic for Integrative Dentistry, Munich, Germany; 2Center for Integrative Healing, Wuppertal, Germany; 3Statistics at Institute for Epidemiological Studies, Berlin, Germany Background: Recent ...
Lechner J, Aschoff J, Rudi T
doaj  

Interplay of integrins and selectins in metastasis

open access: yesMolecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva   +2 more
wiley   +1 more source

Clinical analysis of anti⁃leucine⁃rich glioma⁃inactivated 1 antibody⁃related encephalitis

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2020
Objective To explore the clinical characteristics of anti⁃leucine⁃rich glioma⁃inactivated 1 (LGI1) antibody⁃related encephalitis. Methods and Results Clinical data of 6 patients with anti⁃LGI1 antibody⁃related encephalitis from September 2016 to April ...
Qing⁃qing ZHAO   +4 more
doaj  

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