Results 181 to 190 of about 3,749,228 (399)

How the immune system shapes atherosclerosis: roles of innate and adaptive immunity

Nature reviews. Immunology, 2021
P. Roy, Marco Orecchioni, K. Ley
semanticscholar   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Assignment: Saving Lives, Speculative Writing on #theCoIncidence of #Asthma Hospitalizations and #COVID-19 Disease, ... Ongoing Reflections on Sars-CoV-2, A Compromised Immune System and Risk Assessment

, 2020
Kevin Moses
openalex   +1 more source

Altered CNS–immune system crosstalk and its link to disease severity in multiple sclerosis

, 2022
Jelena Brasanac, Stefan Hetzer, Susanna Asseyer, Joseph Kuchling, Judith Bellmann–Strobl, Kerstin Ritter, Stefanie Gamradt, Michael Scheel, John­–Dylan Haynes, AU Brandt, Friedemann Paul, Stefan M. Gold, Martin Weygandt   +12 more
openalex   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Lymphoproliferation and hyper-IgM as the first manifestation of activated phosphoinositide 3-kinase δ syndrome: A case report

Biomédica: revista del Instituto Nacional de Salud
Activated phosphoinositide 3-kinase δ syndrome is an inborn error of immunity due to mutations within the genes responsible for encoding PI3Kδ subunits.
Mónica Fernandes-Pineda, Andrés F. Zea-Vera   +1 more
doaj   +1 more source

Christ Bearing the Cross: The Original Antigenic Sin of the Immune System and Its Potential Role in Emerging Diseases [PDF]

, 2023
Ger T. Rijkers, Frans J. van Overveld
openalex   +1 more source

Immune system and cardiovascular disease [PDF]

Nature Reviews Cardiology, 2016
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Immune system responses in Parkinson's disease: Early and dynamic

, 2018
Malú G. Tansey, Marina Romero‐Ramos
openalex   +2 more sources