Results 181 to 190 of about 3,492,274 (391)
Erratum: Sequence Space Localization in the Immune System Response to Vaccination and Disease [Phys. Rev. Lett.91, 068101 (2003) [PDF]
, 2003 Michael W. Deem, Ha Youn Lee
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Guardians at the Gate: Immune System in Gastrointestinal Diseases
International Journal of Molecular SciencesThe immune system plays a key role in gastrointestinal (GI) pathologies, being responsible for protecting the body against infection, maintaining homeostasis, and regulating the inflammatory response in the GI tract [...]
Elena Layunta +2 more
openaire +4 more sources
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
The Potential Roles of Interferon in Managing Viral Diseases in Crustacean [PDF]
, 2011 World crustacean aquaculture has developed considerably since the 1980\u27s and is now worth more than USD 10 billion per year. However, the economic growth of this industry has been severely affected by problems related to diseases and environmental ...
Harpeni, E. (Esti)
core
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
Rebuilding an Immune-Mediated Central Nervous System Disease: Weighing the Pathogenicity of Antigen-Specific versus Bystander T Cells [PDF]
, 2004 Dorian B. McGavern, Phi Truong
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Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Associating Changes in the Immune System with Clinical Diseases for Interpretation in Risk Assessment [PDF]
, 2004 Michael I. Luster +5 more
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Molecular Oncology, EarlyView.In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
wiley +1 more source