Results 181 to 190 of about 3,483,015 (354)
Global Role of the Immune System in Identifying Cancer Initiation and Limiting Disease Progression [PDF]
Mary L. Disis, H. Kim Lyerly
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Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson+11 more
wiley +1 more source
Neuroimmunology is one of the most potential fields of brain science, which challenges the neurologists. The development of antibody spectrum, the deepening research of mechanism and the precision of treatment make the future of this field full of ...
Sheng CHEN, Qin⁃ming ZHOU, You NI
doaj
The unified immune system: Respiratory tract–nasobronchial interaction mechanisms in allergic airway disease [PDF]
Gert‐Jan Braunstahl
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This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani+14 more
wiley +1 more source
Can the immune system fight Alzheimer disease? [PDF]
Bradley T. Hyman, John H. Growdon
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B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez+17 more
wiley +1 more source
Early Immune Activation Predicts Central Nervous System Disease in HIV‐Infected Infants: Implications for Early Treatment [PDF]
Andrea Kovács
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