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The immune system and neuropsychiatric diseases
International Review of Psychiatry, 2005The immune system has a complex and dynamic relationship with the nervous system, both in health and disease. The immune system surveys the central and peripheral nervous systems, becoming activated in response to foreign substances, infectious particles or neoplasms.
Douglas, Kerr +3 more
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How the immune system shapes neurodegenerative diseases
Trends in Neurosciences, 2022Neurodegenerative diseases are a major cause of death and disability worldwide and are influenced by many factors including age, genetics, and injuries. While these diseases are often thought to result from the accumulation and spread of aberrant proteins, recent studies have demonstrated that they can be shaped by the innate and adaptive immune system.
Hannah D. Mason, Dorian B. McGavern
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MicroRNAs, the immune system and rheumatic disease
Nature Clinical Practice Rheumatology, 2008MicroRNAs (miRNAs) are short noncoding RNA molecules that modulate the expression of multiple target genes at the post-transcriptional level and are implicated in a wide array of cellular and developmental processes. In hematopoietic cells, miRNA levels are dynamically regulated during lineage differentiation and also during the course of the immune ...
Esmerina, Tili +3 more
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Atopic disease, immune system, and the environment
Allergy and Asthma Proceedings, 2007Raised prevalence of allergic respiratory diseases observed in the last 20 years seems to be associated with changes of environment and lifestyle, which favor a delayed acquisition of Th1 function in childhood. The purpose of this study is to review recent knowledge concerning the developing human immune system and its interaction with external ...
LEONARDI S +3 more
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Systemic immune aberrations in Alzheimer's disease patients
Journal of Neuroimmunology, 2008The role of chronic inflammation in the pathogenesis of Alzheimer's disease (AD) has been implied in a plethora of studies. The objective of the present study was to evaluate the immune alterations and the immunological markers in patients suffering from AD.
Konstantinos, Bonotis +5 more
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Biologics in Inflammatory Immune-mediated Systemic Diseases
Current Pharmaceutical Biotechnology, 2018The use of biologic agents in systemic immune-mediated diseases has dramatically increased in recent years, replacing conventional immunosuppressive strategies that are characterized by unspecific mechanisms of action and burdened with serious adverse effects.
Gianluca, Moroncini +3 more
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The immune system: primary immune deficiency diseases.
Le Journal medical libanais. The Lebanese medical journal, 2005Table 1 summarizes the major IDD and the methods used for their diagnosis and treatment. The clue to the diagnosis of IDD remains a high index of suspicion when one encounters a child or an adult with recurrent infections. IDD must be relatively common in Lebanon because of the high rate of interfamily marriages.
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