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The role of the immune system in Alzheimer’s disease

Ageing Research Reviews, 2021
Alzheimer's disease (AD) is the most common neurodegenerative disorder where the accumulation of amyloid plaques and the formation of tau tangles are the prominent pathological hallmarks. Increasing preclinical and clinical studies have revealed that different components of the immune system may act as important contributors to AD etiology and ...
Kai-Min Wu   +5 more
openaire   +3 more sources

Prion Diseases and the Immune System

Clinical Immunology, 2000
Transmissible spongiform encephalopathies are caused by unusual infectious agents that are purported to contain a single type of macromolecule, a modified host glycoprotein. The term prion has been applied to this group of agents. Surprisingly, the immune system appears to behave as a Trojan's horse rather than a protective fortification during prion ...
Richard I. Carp   +3 more
openaire   +2 more sources

The immune system and neuropsychiatric diseases

International Review of Psychiatry, 2005
The immune system has a complex and dynamic relationship with the nervous system, both in health and disease. The immune system surveys the central and peripheral nervous systems, becoming activated in response to foreign substances, infectious particles or neoplasms.
Chitra Krishnan   +3 more
openaire   +3 more sources

Atopic disease, immune system, and the environment

Allergy and Asthma Proceedings, 2007
Raised prevalence of allergic respiratory diseases observed in the last 20 years seems to be associated with changes of environment and lifestyle, which favor a delayed acquisition of Th1 function in childhood. The purpose of this study is to review recent knowledge concerning the developing human immune system and its interaction with external ...
LEONARDI S   +3 more
openaire   +4 more sources

Ascorbic acid: its role in immune system and chronic inflammation diseases.

Mini-Reviews in Medical Chemistry, 2014
Ascorbic acid (AA), also known as vitamin C, was initially identified as the factor preventing the scurvy disease, and became very popular for its antioxidant properties.
A. Sorice   +5 more
semanticscholar   +1 more source

MicroRNAs, the immune system and rheumatic disease

Nature Clinical Practice Rheumatology, 2008
MicroRNAs (miRNAs) are short noncoding RNA molecules that modulate the expression of multiple target genes at the post-transcriptional level and are implicated in a wide array of cellular and developmental processes. In hematopoietic cells, miRNA levels are dynamically regulated during lineage differentiation and also during the course of the immune ...
Stefan Costinean   +4 more
openaire   +3 more sources

The maternal immune system in health and disease

Current Opinion in Obstetrics and Gynaecology, 1998
Recent studies have clarified some characteristics of trophoblast and immune cells in the decidua and peripheral blood during pregnancy and the roles they play in the maternal immune system, and have added further evidence to the theory that maternal T helper cell type 1/2 cytokine balance shifts towards T helper cell type 2 dominance during pregnancy.
Yoshinori Iwatani, Mikio Watanabe
openaire   +3 more sources

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