Results 131 to 140 of about 2,034,935 (392)

Case‐Based Immunology: B Cells and Systemic Sclerosis Interstitial Lung Disease

Arthritis &Rheumatology, EarlyView.
Interstitial lung disease (ILD) is an important complication of systemic sclerosis (SSc), with high mortality and morbidity. Recent clinical studies in SSc‐ILD have led to US Food and Drug Administration–approved therapies in SSc‐ILD. Importantly, evidence from these studies has been extrapolated to guide management of ILDs of other systemic autoimmune
Nina Goldman, Voon Ong, Christopher P. Denton   +2 more
wiley   +1 more source

TNFAIP3 Gene Polymorphisms and the Risk of Thrombocytopenia: A Cross‐Sectional Study in Iranian Population

Health Science Reports
Introduction Thrombocytopenia, particularly immune thrombocytopenic purpura, is a prevalent hematological disorder characterized by low platelet counts, leading to increased bleeding risks.
Sorour Alizadeh Saadooni, Zeinab Eftekhar, Mohammad Ali Jalali Far, Najmaldin Saki, Gholam Abbas Kydani, Hossein Karimpourian, Ali Aminasnafi   +6 more
doaj   +1 more source

Does Gestational Thrombocytopenia and Immune Thrombocytopenic Purpura Warrant Hospital Admission?

Pakistan Armed Forces Medical Journal
Objective: To determine the severity of thrombocytopenia in pregnancy and manage gestational thrombocytopenia patients in the outpatient department in order to reduce the economic burden on hospitals. Study Design: Cross-sectional study.
Ayesha Ellahi, Ayesha Nayyar, Maham Arshad, Wasiullah Khan, Afnan Naeem, Warda Furqan   +5 more
doaj   +1 more source

Comparative Efficacy and Safety of Anakinra and Canakinumab in Patients With VEXAS Syndrome: An International Multicenter Study

Arthritis &Rheumatology, EarlyView.
Objective The aim of this study was to compare differences in clinical response, drug survival, and adverse event rates between anakinra and canakinumab in VEXAS (vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic) syndrome. Methods This multicenter international study includes patients with VEXAS from France, Israel, and Italy treated with ...
Tali Eviatar, Dafne Capelusnik, Corrado Campochiaro, Valentin Lacombe, Vincent Jachiet, Michael Zisapel, Iftach Sagy, Oshrat E. Tayer‐Shifman, David Ozeri, Shaye Kivity, Alessandro Tomelleri, Benjamin Terrier, Hagit Peleg, Thibault Comont, Karim Sacre, Pascal Woaye‐Hune, Laurent Arnaud, Estibaliz Lazaro, Vincent Grobost, Francois Lifermann, Maxime Samson, Samuel Ardois, Alice Garnier, Alexandre Maria, Alain Cantagrel, Aurore Meyer, Jean‐David Bouaziz, Mael Heiblig, Lorenzo Dagna, Elisa Diral, Olivier Kosmider, Ori Elkayam, Jérôme Hadjadj, Sophie Georgin‐Lavialle, Olivier Fain, Arsene Mekinian   +35 more
wiley   +1 more source

A Randomized, Placebo‐Controlled Trial of Hydroxychloroquine in Incomplete Lupus

Arthritis &Rheumatology, EarlyView.
Objective Patients with features of systemic lupus erythematosus (SLE) who do not fulfill classification criteria can be designated as incomplete lupus erythematosus (ILE). This condition includes individuals with a high risk of progression to SLE. Treatment of ILE may reduce symptoms, severity, and incidence of SLE.
Nancy J. Olsen, Duanping Liao, Judith A. James, Joel M. Guthridge, Cristina Arriens, Diane Kamen, Mariko Ishimori, Daniel J. Wallace, Christopher Striebich, Sonali Narain, Benjamin F. Chong, Fan He, Eric W. Schaefer, Vernon M. Chinchilli, David R. Karp   +14 more
wiley   +1 more source

The Centenary of Immune Thrombocytopenia—Part 2: Revising Diagnostic and Therapeutic Approach

Frontiers in Pediatrics, 2017
Primary immune thrombocytopenia (ITP) is the most common cause of thrombocytopenia in children and adolescents and can be considered as a paradigmatic model of autoimmune disease. This second part of our review describes the clinical presentation of ITP,
Rita Consolini, Giorgio Costagliola, Davide Spatafora   +2 more
doaj   +1 more source

Clinical characteristics, management and outcome of COVID‐19‐associated immune thrombocytopenia: a French multicentre series

British Journal of Haematology, 2020
The causes of secondary immune thrombocytopenia (ITP), which account for approximately 18 to 20% of all adult ITP cases, include some viral infections (Cines et al, 2009; Moulis et al, 2014).
M. Mahévas, G. Moulis, E. Andrès, E. Rivière, M. Garzaro, Étienne Crickx, V. Guillotin, M. Malphettes, L. Galicier, N. Noel, L. Darnige, L. Terriou, C. Guerveno, M. Sanchis-Borja, T. Moulinet, B. Meunier, M. Ebbo, M. Michel, B. Godeau   +18 more
semanticscholar   +1 more source

Platelets promote macrophage polarization toward pro-inflammatory phenotype and increase survival of septic mice [PDF]

, 2019
We investigated the contribution of human platelets to macrophage effector properties in the presence of lipopolysaccharide (LPS), as well as the beneficial effects and time frame for platelet transfusion in septic animals.
Carestia, Agostina, Carrera Silva, Eugenio Antonio, Errasti, Andrea Emilse, Gomez, Ricardo Martin, Jenne, Craig N., Mena, Hebe Agustina, Negrotto, Soledad, Olexen, Cinthia Mariel, Ortiz Wilczyñski, Juan Manuel, Schattner, Mirta Ana   +9 more
core   +1 more source

Efficacy of Telitacicept in Childhood‐Onset Systemic Lupus Erythematosus: A Prospective Multicenter Cohort Study With Inverse Probability of Treatment Weighting –Adjusted Comparison to a Historical Control Group Treated With Belimumab

Arthritis &Rheumatology, EarlyView.
Objective The therapeutic effects of telitacicept combined with standard of care (SoC) in childhood‐onset systemic lupus erythematosus (cSLE) remain unclear. This study aims to evaluate its efficacy in comparison with belimumab combined with SoC.
Chong Luo, Shu Su, Jingyue Liu, Junyu Lin, Jin Song, Zongwen Chen, Yuanyuan Peng, Lijun Jiang, Meng Jia, Li Wang, Xinhui Jiang, Wei Zhang, Zanhua Rong, Bo Zhao, Yajun Wang, Xuemei Tang   +15 more
wiley   +1 more source

Clinical Aspects of Feline Retroviruses: A Review [PDF]

, 2012
Feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV) are retroviruses with global impact on the health of domestic cats. The two viruses differ in their potential to cause disease.
Ackley, Anderson, Barlough, Barnett, Barr, Beatty, Beatty, Beatty, Bishop, Bishop, Brightman, Brown, Callanan, Callanan, Carmichael, Choi, Cotter, Cotter, Cotter, Court, Cullen, Day, Dean, Diehl, Dow, Ellis, English, Essex, Fleming, Flynn, Francis, Garg, Gunn-Moore, Hara, Hardy, Harrus, Heit, Hoffmann-Fezer, Hofmann-Lehmann, Holznagel, Hoover, Hoover, Hutson, Jackson, Jarrett, Johnson, Joshi, Katrin Hartmann, Kipar, Kohn, Kubes, Lauring, Levy, Levy, Levy, Liang, Linenberger, Lott-Stolz, Matsumoto, Mitchell, Mizuno, Mizuno, Mizuno, Mortola, Mortola, Novotney, O'Connor, Ohno, Ohno, Overbaugh, Pedersen, Pedersen, Phillips, Phipps, Podell, Podell, Pool, Power, Prospero-Garcia, Quackenbush, Reinacher, Rickard, Ritchey, Rohn, Schrenzel, Sellon, Sellon, Sheets, Shelton, Shelton, Shimojima, Shimojima, Stiles, Taniguchi, Tompkins, Torten, Tsatsanis, Willett, Willett, Zaccaro, Zhao   +100 more
core   +3 more sources