Results 191 to 200 of about 86,262 (260)

Functional validation of a modified platelet desialylation test for immune and hereditary thrombocytopenias

open access: yesTransfusion Medicine, EarlyView.
Abstract Background Thrombocytopenia arises from heterogeneous inherited and acquired disorders, and identifying the underlying platelet clearance mechanisms remains challenging. Platelet desialylation, characterised by loss of sialic acid and consequent exposure of terminal β‐galactose residues recognised by the Ashwell–Morell receptor, represents an ...
Karen Nogueira Chinoca Ziza   +14 more
wiley   +1 more source

Prioritising parameters to minimise blood transfusions for postpartum haemorrhage: A machine learning study using national population data

open access: yesTransfusion Medicine, EarlyView.
Abstract Background Postpartum haemorrhage (PPH) accounts for approximately 27% of maternal deaths worldwide and often requires blood transfusion, along with its associated risks. In resource‐rich settings like South Korea, transfusion disparities persist, highlighting the need for predictive tools to optimise patient blood management (PBM).
Ki Hoon Ahn   +2 more
wiley   +1 more source

Oral lichenoid lesions in CTLA‐4 haploinsufficiency: Targeting IFN‐γ‐driven mucosal immunopathology

open access: yes
Journal of the European Academy of Dermatology and Venereology, EarlyView.
Chen Wang   +11 more
wiley   +1 more source

Identification of Lupus Erythematosus Cells and Ragocytes in Peripheral Blood from a Dog with Systemic Lupus Erythematosus

open access: yesVeterinary Clinical Pathology, EarlyView.
ABSTRACT A 3‐year‐old female‐intact German Shepherd presented for the evaluation of progressive shifting leg lameness, carpal swelling, and weight loss with a poor appetite since adoption about three months prior. Routine blood smear evaluation, lymph node, and synovial fluid cytologies all revealed rare neutrophils with cytoplasmic inclusions ...
Samantha L. Braman   +3 more
wiley   +1 more source

Codocytosis in the Dog: 345 Cases (2020–2022)

open access: yesVeterinary Clinical Pathology, EarlyView.
ABSTRACT Introduction Codocytes, or target cells, are a morphologic variation of erythrocytes characterized by increased membrane surface area relative to volume. In dogs, codocytosis is frequently noted on blood smear evaluation, but its clinical significance remains poorly understood. Objectives To characterize the clinical conditions associated with
Sarena M. Krojanker   +5 more
wiley   +1 more source

Age-related and disease-specific changes in B-cell profiles in older adults with immune thrombocytopenia. [PDF]

open access: yesFront Immunol
Monzón Manzano E   +15 more
europepmc   +1 more source

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