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Immune Thrombocytopenic Purpura in Pregnancy
Obstetrical & Gynecological Survey, 2019Importance Immune thrombocytopenia purpura (ITP), an autoimmune disease characterized by destruction of platelets, is a hematological disorder that can present in both pregnant and nonpregnant patients. Although thrombocytopenia in pregnancy can be caused by more common pathologies such as gestational thrombocytopenia and ...
Amanda M, Baucom +2 more
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Immune Thrombocytopenic Purpura and Pregnancy
New England Journal of Medicine, 1982Neonatal thrombocytopenia is a potentially life-threatening complication of immune thrombocytopenic purpura (ITP). We followed 23 pregnant women who had either a history of ITP (11 women) or clinically active disease (12 women) to delineate the factors responsible for neonatal thrombocytopenia.
D B, Cines +4 more
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Immune thrombocytopenic purpura in pregnancy
Current Opinion in Hematology, 2007This review assesses the need for revision of the present guidelines for immune thrombocytopenic purpura in pregnancy based on evidence-based data from published articles of relevance.The American Society of Hematology (ASH) and British Committee for Standards in Haematology (BCSH) guidelines indicate that at platelet counts below 70,000 or 80,000 ...
Terry, Gernsheimer, Keith R, McCrae
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Splenectomy for Immune Thrombocytopenic Purpura
Archives of Surgery, 1981Of 481 splenectomies performed at the University of Utah, Salt Lake City, 78 (16.2%) were for immune (idiopathic) thrombocytopenic purpura (ITP). The mean platelet count prior to therapy was 13,800/cu mm (range, 500 to 80,000/cu mm). All but two patients were initially treated with corticosteroids, and 58.2% responded with an increase in platelets ...
S J, Mintz +4 more
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Immune Thrombocytopenic Purpura in Infants
Archives of Pediatrics & Adolescent Medicine, 1994Acute immune thrombocytopenic purpura (ITP) is a well-described illness in preschool and young school-aged children and is usually self-limited. It has been suggested that infants with acute ITP do not respond to conventional therapy as well as children between ages 1 and 8 years and are more likely to Comparison of Acute Immune Thrombocytopenic ...
J D, Hord, J A, Whitlock, N J, Grossman
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The epidemiology of immune thrombocytopenic purpura
Current Opinion in Hematology, 2007This review updates the American Society of Hematology and British guidelines on immune thrombocytopenic purpura incidence, prevalence, and natural history, with recent observations from the peer-reviewed medical literature.This analysis was conducted using literature-indexing systems to identify relevant articles.
Patrick F, Fogarty, Jodi B, Segal
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Immune thrombocytopenic purpura
Postgraduate Medicine, 1977Idiopathic thrombocytopenia is one of the most common hematologic disorders. It has many causes, most of which precipitate an immunologic reaction that results in immune thrombocytopenic purpura. A systematic approach to diagnosis and therapy is important.
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Secondary immune thrombocytopenic purpura
Current Opinion in Hematology, 2007The American Society of Hematology and British Committee for Standards in Haematology guidelines for the diagnosis and management of immune thrombocytopenic purpura focused entirely on primary disease, and secondary forms were not addressed. The guidelines did not address thrombocytopenia resulting from autoimmune disorders or chronic infections such ...
Howard A, Liebman, Roberto, Stasi
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Immune Thrombocytopenic Purpura ITP
Vox Sanguinis, 1998AbstractImmune thrombocytopenic purpura ITP is characterized by early platelet destruction due to an unbalanced immune response. In acute ITP, a transient increase of HLA‐DR molecules has been detected while in individuals with chronic ITP, in addition, increased serum concentrations of IL‐2 and other cytokines reflecting in vivo T‐cell activation have
Imbach P, Kühne T
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The Pathogenesis of Immune Thrombocytopenic Purpura
CRC Critical Reviews in Clinical Laboratory Sciences, 1977Chronic idiopathic thrombocytopenic purpura (ITP) is a human disease manifested by destructive thrombocytopenia due to a circulating antiplatelet antibody. The antibody is of IgG type and is produced primarily in the spleen and bone marrow. After binding of the antibody to a platelet-associated antigen, phagocytosis is triggered either via the Fc ...
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