Results 181 to 190 of about 26,471 (221)
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Splenectomy for Immune Thrombocytopenic Purpura
Archives of Surgery, 1981Of 481 splenectomies performed at the University of Utah, Salt Lake City, 78 (16.2%) were for immune (idiopathic) thrombocytopenic purpura (ITP). The mean platelet count prior to therapy was 13,800/cu mm (range, 500 to 80,000/cu mm). All but two patients were initially treated with corticosteroids, and 58.2% responded with an increase in platelets ...
S J, Mintz +4 more
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Immune Thrombocytopenic Purpura in Infants
Archives of Pediatrics & Adolescent Medicine, 1994Acute immune thrombocytopenic purpura (ITP) is a well-described illness in preschool and young school-aged children and is usually self-limited. It has been suggested that infants with acute ITP do not respond to conventional therapy as well as children between ages 1 and 8 years and are more likely to Comparison of Acute Immune Thrombocytopenic ...
J D, Hord, J A, Whitlock, N J, Grossman
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Immune thrombocytopenic purpura in pregnancy
Current Opinion in Hematology, 2007This review assesses the need for revision of the present guidelines for immune thrombocytopenic purpura in pregnancy based on evidence-based data from published articles of relevance.The American Society of Hematology (ASH) and British Committee for Standards in Haematology (BCSH) guidelines indicate that at platelet counts below 70,000 or 80,000 ...
Terry, Gernsheimer, Keith R, McCrae
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Immune Thrombocytopenic Purpura and Pregnancy
New England Journal of Medicine, 1982Neonatal thrombocytopenia is a potentially life-threatening complication of immune thrombocytopenic purpura (ITP). We followed 23 pregnant women who had either a history of ITP (11 women) or clinically active disease (12 women) to delineate the factors responsible for neonatal thrombocytopenia.
D B, Cines +4 more
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Immune thrombocytopenic purpura in adults
Current Opinion in Hematology, 2007A review of recent studies was conducted to determine if guidelines promulgated by the American Society of Hematology and the British Committee for Standards in Haematology need to be updated as these were based mainly on expert opinion rather than outcomes derived from clinical trials.Recent studies suggest that most patients with immune ...
Bertrand, Godeau +2 more
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Chronic immune thrombocytopenic purpura
Hämostaseologie, 2009SummaryFirst generation thrombopoietic growth factors (rhTPO and PEG-rHuMGDF), investigated in the early 2000s, proved effective in increasing platelet count in normal volunteers, in thrombocytopenia due to chemotherapy and also in a few cases of immune thrombocytopenic purpura (ITP).
F, Rodeghiero, M, Ruggeri
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Immune Thrombocytopenic Purpura in Pregnancy
Obstetrical & Gynecological Survey, 2019Importance Immune thrombocytopenia purpura (ITP), an autoimmune disease characterized by destruction of platelets, is a hematological disorder that can present in both pregnant and nonpregnant patients. Although thrombocytopenia in pregnancy can be caused by more common pathologies such as gestational thrombocytopenia and ...
Amanda M, Baucom +2 more
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Immune Thrombotic Thrombocytopenic Purpura
JAMAImportanceImmune thrombotic thrombocytopenic purpura (iTTP) is a life-threatening thrombotic microangiopathy that presents with microangiopathic hemolytic anemia (MAHA) and thrombocytopenia. Worldwide annual incidence of iTTP is 2 cases per million to 6 cases per million.ObservationsImmune TTP is caused by an autoantibody to a disintegrin and ...
Allyson M, Pishko, Ang, Li, Adam, Cuker
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Viral-Associated Immune Thrombocytopenic Purpura
Hematology, 2008Abstract Chronic immune thrombocytopenic purpura (CITP) is a diagnosis of exclusion that occurs either de novo or secondary to other underlying disorders. Chronic infection with human immunodeficiency virus (HIV) and hepatitis C virus (HCV) are now well-characterized causes of CITP.
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Pathophysiology of immune thrombocytopenic purpura
Blood Reviews, 2002In 1951, the young hematologist in training, Dr. William Harrington, infused himself with plasma from a patient with immune thrombocytopenic purpura (ITP). He rapidly developed severe, but transient, thrombocytopenia and was at risk for serious hemorrhage. Thus, the humoral autoimmune cause of ITP was established. Since 1953, when Dr.
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