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Immune Thrombocytopenic Purpura in Infants
Archives of Pediatrics & Adolescent Medicine, 1994Acute immune thrombocytopenic purpura (ITP) is a well-described illness in preschool and young school-aged children and is usually self-limited. It has been suggested that infants with acute ITP do not respond to conventional therapy as well as children between ages 1 and 8 years and are more likely to Comparison of Acute Immune Thrombocytopenic ...
James A. Whitlock+2 more
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Immune thrombocytopenic purpura
Pathology, 2010The disease that was formerly termed idiopathic thrombocytopenia (ITP), is becoming far better understood, so much so that the same acronym has been reworked, to mean immune thrombocytopenia. Recent progress using murine models of the disease has shed new insights into the mechanisms of platelet destruction (both B and T cell mediated), and have lead ...
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Immune thrombocytopenic purpura in pregnancy
Current Opinion in Hematology, 2007This review assesses the need for revision of the present guidelines for immune thrombocytopenic purpura in pregnancy based on evidence-based data from published articles of relevance.The American Society of Hematology (ASH) and British Committee for Standards in Haematology (BCSH) guidelines indicate that at platelet counts below 70,000 or 80,000 ...
Terry Gernsheimer, Keith R. McCrae
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Immune Thrombocytopenic Purpura
Medical Clinics of North America, 1980ITP is a hemorrhagic disorder in which thrombocytopenia is associated with increased peripheral destruction of platelets. It is a syndrome of different diseases, all of which have in common shortened platelet survival owing to the presence of an antiplatelet antibody. Most cases are secondary to an identifiable etiologic agent.
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Immune thrombocytopenic purpura in adults
Current Opinion in Hematology, 2007A review of recent studies was conducted to determine if guidelines promulgated by the American Society of Hematology and the British Committee for Standards in Haematology need to be updated as these were based mainly on expert opinion rather than outcomes derived from clinical trials.Recent studies suggest that most patients with immune ...
Drew Provan+2 more
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Immune Thrombocytopenic Purpura in Pregnancy
Obstetrical & Gynecological Survey, 2019Importance Immune thrombocytopenia purpura (ITP), an autoimmune disease characterized by destruction of platelets, is a hematological disorder that can present in both pregnant and nonpregnant patients. Although thrombocytopenia in pregnancy can be caused by more common pathologies such as gestational thrombocytopenia and ...
Sarah K. Dotters-Katz+2 more
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Immune Thrombocytopenic Purpura ITP
Vox Sanguinis, 1998AbstractImmune thrombocytopenic purpura ITP is characterized by early platelet destruction due to an unbalanced immune response. In acute ITP, a transient increase of HLA‐DR molecules has been detected while in individuals with chronic ITP, in addition, increased serum concentrations of IL‐2 and other cytokines reflecting in vivo T‐cell activation have
Paul Imbach, Thomas Kühne
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Immune thrombocytopenic purpura
Postgraduate Medicine, 1977Idiopathic thrombocytopenia is one of the most common hematologic disorders. It has many causes, most of which precipitate an immunologic reaction that results in immune thrombocytopenic purpura. A systematic approach to diagnosis and therapy is important.
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The epidemiology of immune thrombocytopenic purpura
Current Opinion in Hematology, 2007This review updates the American Society of Hematology and British guidelines on immune thrombocytopenic purpura incidence, prevalence, and natural history, with recent observations from the peer-reviewed medical literature.This analysis was conducted using literature-indexing systems to identify relevant articles.
Jodi B Segal, Patrick F. Fogarty
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Secondary immune thrombocytopenic purpura
Current Opinion in Hematology, 2007The American Society of Hematology and British Committee for Standards in Haematology guidelines for the diagnosis and management of immune thrombocytopenic purpura focused entirely on primary disease, and secondary forms were not addressed. The guidelines did not address thrombocytopenia resulting from autoimmune disorders or chronic infections such ...
Howard A. Liebman, Roberto Stasi
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