Results 251 to 260 of about 54,639 (294)

Alternate‐day dosing of caplacizumab for immune‐mediated thrombotic thrombocytopenic purpura

Journal of Thrombosis and Haemostasis, 2022
The anti‐von Willebrand factor (VWF) nanobody caplacizumab directly prevents the fatal microthrombi formation in immune‐mediated thrombotic thrombocytopenic purpura (iTTP), thereby adding a new therapeutic principle to the treatment of this disorder ...
Lucas Kühne   +14 more
semanticscholar   +1 more source

Immune Thrombocytopenic Purpura

New England Journal of Medicine, 2002
Immune thrombocytopenic purpura, which may lead to bleeding, is typically caused by antibodies directed against the platelet glycoprotein IIb/IIIa complex. Since the management of the disorder is different for children and adults, the authors of this up-to-date review provide separate sections on the two age groups.
Douglas B. Cines, Victor S. Blanchette
openaire   +5 more sources

Immune Thrombocytopenic Purpura

Hematology/Oncology Clinics of North America, 2007
Immune thrombocytopenic purpura (ITP) is an autoantibody-mediated thrombocytopenic disorder in which accelerated destruction of platelets occurs; platelet production may also be impaired by these antibodies. ITP is characterized by mucocutaneous bleeding. Rarely, more severe hemorrhages, such as intracranial hemorrhage, may occur. Traditional therapies,
James B. Bussel, Bethan Psaila
openaire   +5 more sources

Incidence, diagnosis, and outcome of immune‐mediated thrombotic thrombocytopenic purpura: A nationwide survey by the Spanish registry of thrombotic thrombocytopenic purpura

Journal of clinical apheresis, 2021
Immune‐mediated thrombotic thrombocytopenic purpura (iTTP) is a rare disease characterized by the presence of anti‐ADAMTS13 autoantibodies. Achieving accurate information on incidence and customary disease management is important to provide appropriate ...
C. Pascual-Izquierdo   +21 more
semanticscholar   +1 more source

Immune thrombocytopenic purpura

The Indian Journal of Pediatrics, 2008
Immune thrombocytopenic purpura (ITP) is the commonest cause of sudden onset thrombocytopenia in a healthy child. The condition is frequently preceded by a viral infection. The hematological parameters are essentially normal except a low platelet count. Bone marrow examination is not routinely indicated except in specific situations.
B. D. Bhatia, Vineeta Gupta, V. Tilak
openaire   +3 more sources

Immune Thrombocytopenic Purpura

JCR: Journal of Clinical Rheumatology, 1997
Thrombocytopenia is seen commonly in patients with rheumatic disorders. In general, thrombocytopenia is due to one of three mechanisms: reduced production, sequestration, or increased platelet destruction. In outpatients, the most common cause of thrombocytopenia is immune thrombocytopenia. Immune thrombocytopenia encompasses a broad group of disorders
Mark Crowther, John G. Kelton
openaire   +3 more sources

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