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Immune thrombocytopenic purpura in adults
Current Opinion in Hematology, 2007A review of recent studies was conducted to determine if guidelines promulgated by the American Society of Hematology and the British Committee for Standards in Haematology need to be updated as these were based mainly on expert opinion rather than outcomes derived from clinical trials.Recent studies suggest that most patients with immune ...
Drew Provan +2 more
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Immune thrombocytopenic purpura
Postgraduate Medicine, 1977Idiopathic thrombocytopenia is one of the most common hematologic disorders. It has many causes, most of which precipitate an immunologic reaction that results in immune thrombocytopenic purpura. A systematic approach to diagnosis and therapy is important.
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Immune Thrombocytopenic Purpura in Pregnancy
Obstetrical & Gynecological Survey, 2019Importance Immune thrombocytopenia purpura (ITP), an autoimmune disease characterized by destruction of platelets, is a hematological disorder that can present in both pregnant and nonpregnant patients. Although thrombocytopenia in pregnancy can be caused by more common pathologies such as gestational thrombocytopenia and ...
Sarah K. Dotters-Katz +2 more
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The epidemiology of immune thrombocytopenic purpura
Current Opinion in Hematology, 2007This review updates the American Society of Hematology and British guidelines on immune thrombocytopenic purpura incidence, prevalence, and natural history, with recent observations from the peer-reviewed medical literature.This analysis was conducted using literature-indexing systems to identify relevant articles.
Jodi B Segal, Patrick F. Fogarty
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Secondary immune thrombocytopenic purpura
Current Opinion in Hematology, 2007The American Society of Hematology and British Committee for Standards in Haematology guidelines for the diagnosis and management of immune thrombocytopenic purpura focused entirely on primary disease, and secondary forms were not addressed. The guidelines did not address thrombocytopenia resulting from autoimmune disorders or chronic infections such ...
Howard A. Liebman, Roberto Stasi
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Childhood immune thrombocytopenic purpura
Blood Reviews, 2002Childhood immune thrombocytopenic purpura (ITP) is acute and generally seasonal in nature, suggesting that infectious or environmental agents may trigger the immune response to produce platelet-reactive autoantibodies 4 to 8 weeks following an infection.
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The Pathogenesis of Immune Thrombocytopenic Purpura
CRC Critical Reviews in Clinical Laboratory Sciences, 1977Chronic idiopathic thrombocytopenic purpura (ITP) is a human disease manifested by destructive thrombocytopenia due to a circulating antiplatelet antibody. The antibody is of IgG type and is produced primarily in the spleen and bone marrow. After binding of the antibody to a platelet-associated antigen, phagocytosis is triggered either via the Fc ...
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Pathophysiology of immune thrombocytopenic purpura
Blood Reviews, 2002In 1951, the young hematologist in training, Dr. William Harrington, infused himself with plasma from a patient with immune thrombocytopenic purpura (ITP). He rapidly developed severe, but transient, thrombocytopenia and was at risk for serious hemorrhage. Thus, the humoral autoimmune cause of ITP was established. Since 1953, when Dr.
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Surgical treatment of immune thrombocytopenic purpura
World Journal of Surgery, 1992AbstractThe role of surgery in the treatment of immune thrombocytopenic purpura (ITP) is still discussed. The aim of this study was to verify our criteria of patient selection for splenectomy, to analyze the results of a protocol for the evaluation of the hemorragic risk, and to discuss long‐term results of 70 patients with ITP who underwent surgical ...
CHIRLETTI, Piero +9 more
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Management of immune thrombocytopenic purpura
Paediatrics and Child Health, 2007Abstract Childhood immune thrombocytopenic purpura (ITP) is an uncommon, generally self-limiting, heterogeneous condition usually with a good outlook. Most children recover quickly without serious bleeding complications irrespective of specific treatment to raise the platelet count.
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