Results 61 to 70 of about 54,639 (294)

Autoimmunity and Novel Therapies in Immune-Mediated Thrombocytopenia [PDF]

, 2013
Immune-mediated thrombocytopenic purpura (ITP) is recognized as a cell-specific autoimmune disorder, yet, multifactorial in origin. The development of thrombocytopenia is well proven to be mediated by both humoral (anti-platelet antibodies) and cellular (
Shoenfeld, Yehuda, Toubi, Elias, Vadasz, Zahava, Yehudai, Dana   +3 more
core   +1 more source

Plasma Thrombospondin in Immune Thrombocytopenic Purpura [PDF]

Journal of International Medical Research, 2002
Patients with immune thrombocytopenic purpura (ITP) rarely suffer life-threatening haemorrhages despite significant thrombocytopenia, probably because large numbers of hyperfunctioning platelets are present. Thrombospondin is a platelet α-granule protein and its plasma level may reflect platelet activation.
Özcebe, O.I, Karakuş, S, Haznedaroǧlu, I.C, Göker, H, Kosar, A, Koçoǧlu, H, Büyükaşik, Y, Sayinalp, N, Kirazli, Ş.   +8 more
openaire   +4 more sources

Single course of high dose dexamethasone is more effective than conventional prednisolone therapy in the treatment of primary newly diagnosed immune thrombocytopenia [PDF]

, 2012
INTRODUCTION: Immune thrombocytopenia (ITP) is an immune disorder commonly presents as isolated thrombocytopenia. Generally corticosteroids are the main treatment of ITP.
Ebrahim Miri-Moghaddam, Mahmoud Kaykhaei, Mohammad Mashhadi, Zahra Sepehri   +3 more
core   +2 more sources

The diagnosis and management of the haematologic manifestations of lupus [PDF]

, 2016
Haematological manifestations in systemic lupus erythematosus (SLE) are frequently observed. They are diverse and range from mild to severe.
Castro, SG, Isenberg, DA, Velo-García, A   +2 more
core   +1 more source

Impact of COVID‐19 Vaccination on Menstrual Irregularities, Bleeding Patterns, and Cycle Duration: A Systematic Review and Meta‐Analysis

Health Science Reports, Volume 8, Issue 6, June 2025.
Abstract Background COVID‐19 vaccination has raised concerns regarding its potential effects on women's reproductive health, particularly menstrual irregularities. This systematic review and meta‐analysis aimed to assess the impact of COVID‐19 vaccination on menstrual disturbances, bleeding patterns, and cycle duration among women of reproductive age ...
Ganesh Bushi, Abhay M. Gaidhane, Nasir Vadia, Soumya V. Menon, Kattela Chennakesavulu, Rajashree Panigrahi, Muhammed Shabil, Diptismita Jena, Harish Kumar, Anju Rani, Sanjit Sah, Shivam Rohilla, Mahendra Pratap Singh, Khang Wen Goh   +13 more
wiley   +1 more source

Prognostic and Long-term Survival of Immune Thrombotic Thrombocytopenic Purpura in older patients.

Blood, 2019
Background: Immune Thrombotic Thrombocytopenic Purpura (iTTP) is a potentially lethal auto-immune disease. Older age is associated with increased iTTP mortality. Yet, data are scarce regarding iTTP occurring among older patients and their short- and long-
R. Prével, Claire Roubaud-Roubaud, Samuel Gourlain, M. Jamme, K. Pérès, Y. Benhamou, L. Galicier, É. Azoulay, P. Poullin, F. Provôt, É. Maury, C. Presne, M. Hamidou, S. Saheb, A. Wynckel, A. Servais, S. Girault, Yahsou Delmas, V. Châtelet, J. Augusto, C. Mousson, P. Pérez, J. Halimi, T. Kanouni, A. Lautrette, Anne Charvet Rumpler, C. Deligny, D. Chauveau, A. Veyradier, P. Coppo   +29 more
semanticscholar   +1 more source

Subdural Hematoma in Grave’s Disease Induced Thrombocytopenia. [PDF]

, 2013
Subdural hematoma (SDH) usually occurs secondary to trauma, in bleeding disorders it may occur spontaneously. It is a rare complication of immune thrombocytopenia.
Chandek, S, Diwan, S, Kakani, A, Kumar, S, Nitey, PO   +4 more
core   +1 more source

A case of pulmonary tuberculosis accompanied with immune thrombocytopenic purpura [PDF]

, 2010
A 30-year-old Japanese woman with chest pain and nodules in the left upper lung field was diagnosed as having pulmonary tuberculosis by sputum examination. Purpura on her legs had lasted for 3 months and her platelet count was 1.9 × 104/mm3 on admission.
Fujikawa, Takeya, Inoue, Takako, Kagami, Sin-ichi, Maekura, Ryoji, Mori, Masahide, Namba, Yoshinobu, Sugahara, Hiroyuki, Sugano, Teppei, Yamaguchi, Toshihiko, Yano, Yukihiro, Yokota, Soichiro   +10 more
core   +1 more source

Hetrombopag: A promising thrombopoietin receptor agonist for the treatment of primary and secondary immune thrombocytopenia

Rheumatology &Autoimmunity, Volume 5, Issue 2, Page 101-115, June 2025.
This review seeks to provide a thorough synthesis of the existing literature on the role of thrombopoietin receptor agonists in the treatment of primary and secondary immune thrombocytopenia, with particular emphasis on the compound Hetrombopag. Abstract Immune thrombocytopenia (ITP) is a rare autoimmune disorder characterized by a platelet count below
Jiaqi Hu, Zhida Fu, Xia Xu, Zhengyi Jin, Xinyu Qian, Weiyu Tao, Taiyan Ma, Dongbao Zhao, Jie Gao   +8 more
wiley   +1 more source

Predictors of relapse and efficacy of rituximab in immune thrombotic thrombocytopenic purpura.

Blood Advances, 2019
Patients with immune-mediated thrombotic thrombocytopenic purpura (iTTP) often experience life-threatening relapses of the disease, and rituximab (RTX) can be used to mitigate relapse risk. However, the predictors of relapse in iTTP and the magnitude and
Lova Sun, Johnathan Mack, Ang Li, Justine Ryu, V. Upadhyay, L. Uhl, R. Kaufman, C. Stowell, W. Dzik, R. Makar, Pavan K Bendapudi   +10 more
semanticscholar   +1 more source