Results 251 to 260 of about 327,289 (308)

Macroautophagy in Immunity and Tolerance

Traffic, 2009
Autophagy and proteasomal degradation constitute the two main catabolic pathways in cells. While the proteasome degrades primarily short‐lived soluble proteins, macroautophagy, the main constitutive autophagic pathway, delivers cell organelles and protein aggregates for lysosomal degradation.
Gannagé, M, Münz, C
openaire   +3 more sources

Autophagy and Immune Tolerance

2019
The immune system plays a critical role in defense against invading pathogens, and its function must be strictly controlled to maintain intracellular homeostasis. Once suffering microbial invasion or receiving danger signals, the immune system initiates the responses timely.
Yao-Xing, Wu, Shou-Heng, Jin, Jun, Cui
openaire   +2 more sources

Bile acids for immune tolerance

Science Signaling, 2021
The bacterial bile acid metabolite isoalloLCA stimulates the differentiation of T reg cells.
openaire   +2 more sources

Metabolic reinvigoration of immune tolerance

Nature Reviews Rheumatology, 2021
New research shows that metabolic modulation can restore immune tolerance induction by anti-CD45RB antibodies in lupus-prone mice and reduce systemic lupus erythematosus-like pathology.
openaire   +2 more sources

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