Results 251 to 260 of about 1,952,965 (303)

Induction of immune tolerance in NMOSD and MOGAD. [PDF]

open access: yesTher Adv Neurol Disord
Correale J, Carnero Contentti E.
europepmc   +1 more source

Immune tolerance in allergy

open access: yesCurrent Opinion in Immunology, 2009
Research on the mechanisms of immune regulation in allergy and asthma has shown substantial progress in recent years and has led to a variety of allergen-specific therapeutic and preventive approaches. Studies on the area of allergen-specific immunotherapy (allergen-SIT) have provided substantial knowledge on the mechanisms of allergic disease with ...
Akdis, M, Mübeccel Akdis
openaire   +5 more sources
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Macroautophagy in Immunity and Tolerance

Traffic, 2009
Autophagy and proteasomal degradation constitute the two main catabolic pathways in cells. While the proteasome degrades primarily short‐lived soluble proteins, macroautophagy, the main constitutive autophagic pathway, delivers cell organelles and protein aggregates for lysosomal degradation.
Gannagé, M, Münz, C
openaire   +4 more sources

Tolerance and immune regulation

Immunology Today, 1991
Understanding of both the phenomenon of immunological tolerance and the mechanisms by which it is achieved is rapidly advancing, as was evident from a recent meeting. This report summarizes key developments in both T- and B-cell biology.
Robey, Ellen, Urbain, Jacques
openaire   +3 more sources

Autophagy and Immune Tolerance

2019
The immune system plays a critical role in defense against invading pathogens, and its function must be strictly controlled to maintain intracellular homeostasis. Once suffering microbial invasion or receiving danger signals, the immune system initiates the responses timely.
Yao-Xing, Wu, Shou-Heng, Jin, Jun, Cui
openaire   +2 more sources

Mechanisms of Immune Tolerance to Allergens

2012
In allergic diseases, immune responses are induced by normally well-tolerated allergens, which result in chronic inflammation characterized by antibody secretion and T cell activation. For almost 100 years, allergen-specific immunotherapy (allergen-SIT) has been the potentially curative and antigen-specific method for the treatment of allergic diseases.
Fujita, Hiroyuki   +3 more
openaire   +3 more sources

Tolerance and Immunity in the Intestinal Immune System

Critical Reviews™ in Immunology, 2000
The intestinal immune system must guard the body against invasion by pathogens while avoiding a response to the many potential antigens present in food. In the absence of the inflammatory stimuli necessary to elicit an immune response, oral administration of soluble protein antigens induces antigen-specific systemic nonresponsiveness.
openaire   +2 more sources

Metabolic reinvigoration of immune tolerance

Nature Reviews Rheumatology, 2021
New research shows that metabolic modulation can restore immune tolerance induction by anti-CD45RB antibodies in lupus-prone mice and reduce systemic lupus erythematosus-like pathology.
openaire   +2 more sources

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