Results 171 to 180 of about 22,763 (264)

Vaccination and transfusion safety at the time of expanding use of live attenuated vaccines

open access: yes
Vox Sanguinis, EarlyView.
Pierre Tiberghien   +4 more
wiley   +1 more source

Surface Plasmon Resonance (SPR) Workflow for Comparative Analysis of Nanobody Variants Binding to Lysozyme as a Model Ligand

open access: yesCurrent Protocols, Volume 6, Issue 5, May 2026.
Abstract Developing protein interaction–based technologies such as biosensors requires a clear understanding of receptor‐target kinetics. Nanobodies, which are camelid‐derived single‐domain antibodies, are ideal biosensor receptors due to their high specificity, stability, and ease of production. During biosensor development, multiple nanobody variants
Escarlet Díaz‐Galicia   +5 more
wiley   +1 more source

Geographic and Temporal Variations in Immunization Coverage in Nepal: An Ecological Time‐Trend Analysis

open access: yesHealth Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background Immunization remains a vital public health intervention in Nepal, yet significant disparities persist. This study evaluates the performance of Nepal's national immunization program by analyzing district‐level vaccination coverage and dropout rates from 2009 to 2022 to identify trends and disparities across different routine ...
Kritika Rana   +6 more
wiley   +1 more source

Serological immunity against vaccine‐preventable diseases in children with inflammatory bowel disease at diagnosis

open access: yesJPGN Reports, Volume 7, Issue 2, Page 289-295, May 2026.
Abstract Objectives Patients with inflammatory bowel disease (IBD) are at increased risk of vaccine‐preventable diseases. However, vaccination coverage in this population is often suboptimal. This retrospective study assessed the vaccination status and vaccine serology of children diagnosed with IBD in a high‐income country with broad vaccine access ...
Clara Noble   +4 more
wiley   +1 more source

Global Health Implications of US Exit From WHO and Suspension of Aid

open access: yes
Public Health Challenges, Volume 5, Issue 2, June 2026.
Kenneth Chukwuebuka Egwu   +5 more
wiley   +1 more source

Isocitrate Dehydrogenase Mutations in Cancer: From Bench to Bedside Applications

open access: yesMedComm, Volume 7, Issue 5, May 2026.
Mutant isocitrate dehydrogenase affects multiple cancer types. Alterations in IDH1 and IDH2 result in abnormal enzyme activity, leading to the overproduction of D‐2‐hydroxyglutarate (D‐2HG). This metabolite disrupts cellular metabolism and epigenetic regulation, driving cancer initiation, progression, and metastasis.
Yuhan Fang   +6 more
wiley   +1 more source

Analysis of Mandatory Post‐Marketing Surveillance Studies Supports Revised Regulatory Requirements in Korea

open access: yesPharmacoepidemiology and Drug Safety, Volume 35, Issue 5, May 2026.
ABSTRACT Purpose The objective of this analysis was to determine the contribution to the understanding of product benefit/risk made by non‐randomized, observational post‐marketing surveillance (PMS) studies previously required by the Ministry of Food and Drug Safety (MFDS) re‐examination system and conducted by Pfizer in Korea over 2000–2024. Methods A
Kevin Wolter   +7 more
wiley   +1 more source

Tau‐targeting active immunotherapy slows progression and reduces pathology in mouse models of tauopathy

open access: yesBrain Pathology, Volume 36, Issue 3, May 2026.
The efficacy of the novel anti‐tau active immunotherapy, p5555kb, was tested using two mouse models of tau pathology. p5555kb inoculation increased the survival rate and reduced tau pathology in tau‐overexpressing P301L mice and decreased tau seeding in the brains of C57BL/6 mice injected with human‐purified Alzheimer's disease tau.
Christopher M. Brown   +7 more
wiley   +1 more source

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