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Incidence of severe COVID‐19 in patients with chronic lymphocytic leukaemia or indolent B‐cell non‐Hodgkin lymphoma who received vaccination and pre‐exposure prophylaxis with tixagevimab and cilgavimab in Italy: An observational study by the GIMEMA working party on chronic lymphoproliferative disorders and by the Fondazione Italiana Linfomi

British Journal of Haematology, EarlyView.
Gian Matteo Rigolin, Stefano Soddu, Riccardo Dondolin, Anna Maria Frustaci, Ilaria Scortechini, Francesca Romana Mauro, Francesco Angotzi, Marina Motta, Lydia Scarfò, Andrea Mengarelli, Annamaria Giordano, Sara Martinelli, Caterina Patti, Paolo Sportoletti, Alessandro Sanna, Nilla Maschio, Rossella Riccioni, Clara Virginia Viganò, Agostino Tafuri, Alfonso Piciocchi, Paola Fazi, Stefano Luminari, Andrés J. M. Ferreri, Guido Gini, Paolo Ghia, Antonio Cuneo   +25 more
wiley   +1 more source

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Toxic effects of pesticides on cellular and humoral immunity: an overview

Immunopharmacology and immunotoxicology, 2022
People are exposed to pesticides through food, drinking water, and the environment. These compounds are associated with several disorders, such as inflammatory diseases, rheumatoid arthritis, cancer, and a condition related to metabolic syndrome.
L. Cestonaro, S. Macedo, Y. Piton, S. Garcia, M. Arbo   +4 more
semanticscholar   +1 more source

SARS-CoV-2 vaccination in rituximab-treated patients: B cells promote humoral immune responses in the presence of T-cell-mediated immunity

Annals of the Rheumatic Diseases, 2021
Objectives Evidence suggests that B cell-depleting therapy with rituximab (RTX) affects humoral immune response after vaccination. It remains unclear whether RTX-treated patients can develop a humoral and T-cell-mediated immune response against SARS-CoV ...
D. Mrak, S. Tobudic, M. Koblischke, Marianne Graninger, H. Radner, D. Sieghart, P. Hofer, T. Perkmann, H. Haslacher, R. Thalhammer, S. Winkler, S. Blüml, K. Stiasny, J. Aberle, J. Smolen, L. Heinz, D. Aletaha, M. Bonelli   +17 more
semanticscholar   +1 more source

Innervation of nociceptor neurons in the spleen promotes germinal center responses and humoral immunity.

Cell
Peripheral sensory neurons widely innervate various tissues to continuously monitor and respond to environmental stimuli. Whether peripheral sensory neurons innervate the spleen and modulate splenic immune response remains poorly defined.
Min Wu, Guangping Song, Jianing Li, Zengqing Song, Bing Zhao, Liyun Liang, Wenlong Li, Huaibin Hu, Haiqing Tu, Sen Li, Pei-Yao Li, Biyu Zhang, Wen Wang, Yu Zhang, Wanpeng Zhang, Weifan Zheng, Jiarong Wang, Yuqi Wen, Kai Wang, Ailing Li, T. Zhou, Yuchen Zhang, Huiyan Li   +22 more
semanticscholar   +1 more source

VZV-specific cell-mediated immunity, but not humoral immunity, correlates inversely with the incidence of herpes zoster and the severity of skin symptoms and zoster-associated pain: The SHEZ study.

Vaccine, 2019
Onset of herpes zoster (HZ) is thought to be related to a decline in cell-mediated immunity (CMI). However, until recently, there have been no large-scale prospective studies on the relationship between varicella-zoster virus (VZV)-specific CMI and the ...
H. Asada
semanticscholar   +1 more source

Humoral immunity goes hormonal

Nature Immunology, 2018
Studies of mice demonstrate a link between the female hormone estrogen and protection against bacteremia and sepsis through the induction of natural antibodies to Eshcerichia coli.
Joseph, Chavarria-Smith, Wouter L W, Hazenbos, Menno, van Lookeren Campagne   +2 more
openaire   +2 more sources