Results 1 to 10 of about 173,621 (252)

Humoral immunity in cancer [PDF]

Signal Transduction and Targeted Therapy
Humoral immunity driven by B cells, plasma cells, and antibodies has emerged as a major determinant of tumor control, immune escape, and therapeutic response.
Jeanne Leonard, Marie Duhamel, Michel Salzet   +2 more
doaj   +2 more sources

Humoral Immunity vs. Salmonella

Frontiers in Immunology, 2020
In primary infection with Salmonella, it has been reported—without consideration of Salmonella's functions—that humoral immunity plays no role in the clearance of bacteria.
Akiko Takaya, Koji Tokoyoda, Tomoko Yamamoto   +2 more
exaly   +3 more sources

Establishing humoral immunity to rabies in a person with multiple sclerosis through booster vaccination: A case report [PDF]

Multiple Sclerosis Journal - Experimental, Translational and Clinical
It is known that certain disease-modifying therapies for multiple sclerosis impair humoral immunity; however, data on the effect of therapies on humoral immunity with human diploid cell rabies vaccine is limited.
D Dinov, P Hardeman, J Tessier, PV Sguigna   +3 more
doaj   +2 more sources

Structural insights into the biological functions of the long pentraxin PTX3

Frontiers in Immunology, 2023
Soluble pattern recognition molecules (PRMs) are a heterogenous group of proteins that recognize pathogen- and danger-associated molecular patterns (PAMPs and DAMPs, respectively), and cooperate with cell-borne receptors in the orchestration of innate ...
Anna Margherita Massimino, Filippo Emanuele Colella, Barbara Bottazzi, Antonio Inforzato, Antonio Inforzato   +4 more
doaj   +1 more source

Broadly neutralizing anti-HIV-1 antibodies tether viral particles at the surface of infected cells

Nature Communications, 2022
Broadly neutralizing antibodies (bNAbs) neutralize HIV-1 and exert Fc-dependent activities against infected cells. Here, Dufloo et al. show that bNAbs also block HIV-1 release by trapping viral particles at the surface of infected cells.
Jérémy Dufloo, Cyril Planchais, Stéphane Frémont, Valérie Lorin, Florence Guivel-Benhassine, Karl Stefic, Nicoletta Casartelli, Arnaud Echard, Philippe Roingeard, Hugo Mouquet, Olivier Schwartz, Timothée Bruel   +11 more
doaj   +1 more source

Diverging humoral and cellular immune responses due to Omicron—a national study from the Faroe Islands

Microbiology Spectrum, 2023
Immunity following infection and vaccination with the SARS-CoV-2 Omicron variant is poorly understood. The aim was to investigate immunity assessed with antibody response, neutralizing antibodies (NAbs), and IFN-γ release under different scenarios: in ...
Maria Skaalum Petersen, Laura Pérez-Alós, Sunnvør K. í Kongsstovu, Eina Hansen Eliasen, Cecilie Bo Hansen, Sólrun Larsen, Jóhanna Ljósá Hansen, Rafael Bayarri-Olmos, Jógvan Páll Fjallsbak, Pál Weihe, Peter Garred   +10 more
doaj   +1 more source

Antibody Neutralization of HIV-1 Crossing the Blood-Brain Barrier

mBio, 2020
HIV-1 can cross the blood-brain barrier (BBB) to penetrate the brain and infect target cells, causing neurocognitive disorders as a result of neuroinflammation and brain damage.
Valérie Lorin, Anne Danckaert, Françoise Porrot, Olivier Schwartz, Philippe V. Afonso, Hugo Mouquet   +5 more
doaj   +1 more source

The immune response to the novel coronavirus infection [PDF]

Клиническая практика, 2021
This review summarizes the current knowledge on the humoral and T-cell immunity to the novel coronavirus infection. A special attention is paid to the viral proteins that induce production of antibodies, different types of immunoglobulins and their role ...
Vyacheslav S. Fedorov, Olga N. Ivanova, Inna L. Karpenko, Alexander V. Ivanov   +3 more
doaj   +1 more source

The dysfunction of Tfh cells promotes pediatric recurrent respiratory tract infections development by interfering humoral immune responses

Heliyon, 2023
Recurrent respiratory tract infections (RRTIs) are one of the most common pediatric diseases. Although the pathogenesis of pediatric RRTIs remains unknown, ineffective B cell-dominated humoral immunity has been considered as the core mechanism.
Jun Diao, Huosheng Liu, Hui Cao, Weibin Chen   +3 more
doaj   +1 more source

Effectiveness and Durability of mRNA Vaccine-Induced SARS-CoV-2-Specific Humoral and Cellular Immunity in Severe Asthma Patients on Biological Therapy

Frontiers in Immunology, 2022
Coronavirus disease 2019 (COVID-19) vaccines effectively elicit humoral and cellular immunity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in healthy populations. This immunity decreases several months after vaccination.
Michal Podrazil, Pavla Taborska, Dmitry Stakheev, Michal Rataj, Jan Lastovicka, Alena Vlachova, Petr Pohunek, Jirina Bartunkova, Daniel Smrz   +8 more
doaj   +1 more source