Results 41 to 50 of about 182,481 (302)

PTX3 is expressed in terminal lymphatics and shapes their organization and function

Frontiers in Immunology
IntroductionThe lymphatic system is a multifaceted regulator of tissue homeostasis and an integral part of immune responses. Previous studies had shown that subsets of lymphatic endothelial cells (LEC) express PTX3, an essential component of humoral ...
Andrea Doni, Marina Sironi, Annalisa Del Prete, Annalisa Del Prete, Fabio Pasqualini, Sonia Valentino, Ivan Cuccovillo, Raffaella Parente, Michela Calvi, Antonella Tosoni, Gianluca Vago, Manuela Nebuloni, Cecilia Garlanda, Cecilia Garlanda, Annunciata Vecchi, Barbara Bottazzi, Alberto Mantovani, Alberto Mantovani, Alberto Mantovani   +18 more
doaj   +1 more source

Humoral Immunity across the SARS-CoV-2 Spike after Sputnik V (Gam-COVID-Vac) Vaccination [PDF]

SARS-CoV-2 vaccines have contributed to attenuating the burden of the COVID-19 pandemic by promoting the development of effective immune responses, thus reducing the spread and severity of the pandemic.
Rossana Celeste Jaspe, García Piñero, Alexis H., Mariajose Rodriguez-Nuñez, Nereida Parra-Giménez, Franklin Ennodio Claro, de Waard, Jacobus Henri, Liprandi, Ferdinando, Rangel, Héctor Rafael, Hidalgo, Mariana, Claro, Franklin Ennodio, Mayora, Soriuska, Inirida Belisario, José Luis Zambrano, Jaspe, Rossana Celeste, Ferdinando Liprandi, Parra-Giménez, Nereida, Alexis García, Flor Helene Pujol, Zambrano, José Luis, Garzaro, Domingo José, Pujol, Flor Helene, Belisario, Inirida, Rodríguez-Nuñez, Mariajose, Alejandro Cornejo, Christopher Franco, Jacobus Henri de Waard, Héctor Rafael Rangel, Franco, Christopher, Cornejo, Alejandro, Mariana Hidalgo, Soriuska Mayora, Domingo José Garzaro   +31 more
core   +1 more source

Moderate to severe SARS-CoV-2 infection primes vaccine-induced immunity more effectively than asymptomatic or mild infection

npj Vaccines, 2022
Hybrid immunity induced by vaccination following recovery from SARS-CoV-2 infection is more robust than immunity induced by either infection or vaccination alone.
Kayla A. Holder, Danielle P. Ings, Debbie O. A. Harnum, Rodney S. Russell, Michael D. Grant   +4 more
doaj   +1 more source

Declined Humoral Immunity of Kidney Transplant Recipients to SARS-CoV-2 Vaccines [PDF]

, 2023
Waleed H Mahallawi,1 Wael A Alharbi,1 Sultan A Aloufi,1 Nadir A Ibrahim,1 Muntasir M Abdelrahman,2 Bader A Alhomayeed,2 Moutasem S Aboonq,3 Saeed Awad M Alqahtani,3 Emad S Rajih,4 Abdulaziz M Bakhsh,4 Ibrahim Sandokji5 1Medical Laboratory Technology ...
Aboonq MS, Rajih ES, Abdelrahman MM, Sandokji I, Mahallawi WH, Bakhsh AM, Ibrahim NA, Alhomayeed BA, Alharbi WA, Aloufi SA, Alqahtani SAM   +10 more
core  

Small CD63 + CD81+ extracellular vesicles induce autophagy via the FOXO3a pathway in pancreatic cancer cells during starvation

Scientific Reports
Pancreatic ductal adenocarcinoma (PDAC), the most common histological subtype of pancreatic cancer, is an aggressive malignancy expected to become the second leading cause of cancer-related deaths by 2040.
Daniel Grasso, Maximiliano A. Diaz, Laura Sobrado, Valentín Yzetta, Marcela A. Cucher, Maria L. Cerutti, Daniela L. Papademetrio, Elida Alvarez, Maria Noé Garcia   +8 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Humoral and Cellular Responses in Innate Immunity(Symposium Review) [PDF]

, 2006
The immune system is divided into innate and adaptive immunity. Either immunity consists of humoral and cellular responses, and immunity is maximized when both responses coordinately function.
40172358, 103, 中西, 義信
core   +2 more sources

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Calcineurin inhibitors dampen humoral immunity by acting directly on naive B cells [PDF]

, 2015
Calcineurin inhibitors (CNI), used frequently in solid organ transplant patients, are known to inhibit T cell proliferation, but their effect on humoral immunity is far less studied.
Bogaert, Delfien, Lambrecht, Bart, Dullaers, Melissa, R De Bruyne, Gevaert, P, De Bruyne, R, Van Winckel, M., De Bruyne, R., Gevaert, Philippe, De Ruyck, Natalie, Van Winckel, M, Lambrecht, B. N., M Dullaers, De Ruyck, N., D Bogaert, Bogaert, D, Gevaert, P. (P.), N De Ruyck, Bogaert, D.J.A. (Delfien), M Van Winckel, Dullaers, M., Van Winckel, Myriam, Bogaert, D., De Ruyck, N, P Gevaert, Gevaert, P., B N Lambrecht, De Bruyne, Ruth, Lambrecht, B.N.M. (Bart), Dullaers, M   +29 more
core   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source