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The lipid nanoparticle (LNP)-formulated mRNA vaccines BNT162b2 and mRNA-1273 are a widely adopted multi vaccination public health strategy to manage the COVID-19 pandemic. Clinical trial data has described the immunogenicity of the vaccine, albeit within
Chapin S. Korosec +8 more
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Comparison of the humoral and cellular immunity in COVID-19 convalescents
The SARS-CoV-2 virus caused the COVID-19 pandemic is related to the SARS-CoV-1 and MERS coronaviruses, which were resulted in 2003 and 2012 epidemics. Antibodies in patients with COVID-19 emerge 714 days after the onset of symptoms and gradually increase.
Anna P. Toptygina +3 more
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Humoral Immunity to Hantavirus Infection
Hantaviruses are zoonotic pathogens found in parts of Europe, Asia, South America, and North America, which can cause renal and respiratory failure with fatality rates up to 40%. There are currently no FDA-approved vaccines or therapeutics for hantavirus-
Taylor B. Engdahl, James E. Crowe
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Editorial: Tuberculosis and humoral immunity [PDF]
Taru S. Dutt +1 more
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Innate immunity is an evolutionarily conserved host defense system against infections. The fruit fly Drosophila relies solely on innate immunity for infection defense, and the conservation of innate immunity makes Drosophila an ideal model for ...
Shinzo Iwashita +13 more
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PTX3 is expressed in terminal lymphatics and shapes their organization and function
IntroductionThe lymphatic system is a multifaceted regulator of tissue homeostasis and an integral part of immune responses. Previous studies had shown that subsets of lymphatic endothelial cells (LEC) express PTX3, an essential component of humoral ...
Andrea Doni +18 more
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Interferon Status and Choice of Interferons Inducers in Frequently Ill Children
Literature data on the study of interferon status in children. Own results of the survey group of frequently ill children (FIC) have shown insufficient production of IFN alpha and gamma-IFN, humoral immunity. It was revealed that 66% of the group FIC has
M. S. Savenkovа +5 more
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Pancreatic ductal adenocarcinoma (PDAC), the most common histological subtype of pancreatic cancer, is an aggressive malignancy expected to become the second leading cause of cancer-related deaths by 2040.
Daniel Grasso +8 more
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Hybrid immunity induced by vaccination following recovery from SARS-CoV-2 infection is more robust than immunity induced by either infection or vaccination alone.
Kayla A. Holder +4 more
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The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source

