Results 11 to 20 of about 173,621 (252)
Humoral Immune Response to AAV [PDF]
Frontiers in Immunology, 2013 Adeno-associated virus (AAV) is a member of the family Parvoviridae that has been widely used as a vector for gene therapy because of its safety profile, its ability to transduce both dividing and non-dividing cells, and its low immunogenicity. AAV has been detected in many different tissues of several animal species but has not been associated with ...
Calcedo, Roberto, Wilson, James M.
openaire +3 more sources
Kinetics of severe acute respiratory syndrome coronavirus 2 infection antibody responses
Frontiers in Immunology, 2022 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread rapidly throughout the world, causing severe morbidity and mortality. Since the first reports of Coronavirus disease 2019 (COVID-19) in late 2019, research on the characteristics of ...
Yajie Lin +7 more
doaj +1 more source
Immune correlates of protection following Rift Valley fever virus vaccination
npj Vaccines, 2022 Rift Valley fever virus (RVFV) is a hemorrhagic fever virus with the potential for significant economic and public health impact. Vaccination with an attenuated strain, DelNSsRVFV, provides protection from an otherwise lethal RVFV challenge, but ...
Joshua D. Doyle +3 more
doaj +1 more source
Humoral immunity and bronchiectasis
Clinical and Experimental Immunology, 2002 Summary Bronchiectasis is a common complication of primary antibody deficiency but the incidence of antibody deficiency as an underlying cause of bronchiectasis is largely undefined. In this study the humoral immune status of a cohort of bronchiectatic patients was investigated to detect the frequency of significant antibody deficiency ...
A, Stead +4 more
openaire +3 more sources
Complement and humoral immunity [PDF]
Vaccine, 2008 The complement system was discovered almost a century ago as an important effector in antibody-dependent killing of microorganisms. Since this early period much was learned aboutthe biochemistry and structure of complement proteins and their function in mediating inflammation.
openaire +2 more sources
Pathogens and Immunity, 2021 Background: The role of humoral immunity has been well established in reducing infection risk and facilitating viral clearance in patients with COVID-19. However, the relationship between specific antibody responses and severity of COVID-19 is less well
Jessica Jones +4 more
doaj +1 more source
The role of the immune response in the etiopathogenesis of endometriosis [PDF]
Romanian Medical Journal, 2021 Endometriosis is a benign, chronic, estrogen-dependent condition, present in 10% of women of reproductive age. The condition is associated with chronic pelvic pain and infertility that influence their quality of life, as well as married life and has ...
Catalina Diana Stanica +3 more
doaj +1 more source
Conformational Plasticity in Broadly Neutralizing HIV-1 Antibodies Triggers Polyreactivity
Cell Reports, 2018 Human high-affinity antibodies to pathogens often recognize unrelated ligands. The molecular origin and the role of this polyreactivity are largely unknown.
Julie Prigent +14 more
doaj +1 more source
Elimination of HIV-1-infected cells by broadly neutralizing antibodies
Nature Communications, 2016 Broadly neutralizing antibodies (bNAbs) are promising as potential therapies targeting HIV-1 but their overall antiviral activity remains to be fully elucidated.
Timothée Bruel +12 more
doaj +1 more source
Specific humoral immunity in Osteichthyes
Central European Journal of Immunology, 2018 The fish immune system is extremely complex and has considerable adaptive potential. In Osteichthyes, the system is formed by lymphopoietic organs which are important for the differentiation and maturation of the immune system cells. These organs include
Michał P. Stosik +2 more
doaj +1 more source