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Bacteria and mucosal immunity

Digestive and Liver Disease, 2006
In normal individuals, the intestine is a site of intense immunological activity due to the continuous stimulation by luminal antigens mostly derived from the normal bacterial flora. This is reflected in the huge amount of IgA produced in the gut and the abundant T cells in the lamina propria and epithelium.
MONTELEONE, GIOVANNI   +6 more
openaire   +3 more sources

Oral mucosal immunity

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2013
Oral keratinocytes and dendritic cells of the oral mucosa, through molecular pattern recognition receptors, distinguish between commensal and pathogenic microorganisms and mediate the generation of protective immunoinflammatory responses to potentially invading pathogens or mediate immune tolerance toward commensal microorganisms. Oral immune tolerance
L, Feller   +5 more
openaire   +2 more sources

The development of mucosal immunity

European Journal of Gastroenterology & Hepatology, 2005
The development of the intestinal immune system is a complex sequence of events that begins in utero under various genetic influences, but continues after birth, being modified by factors such as bacteria, hormones and feeds. This review discusses what is known about the ontogeny of each aspect of the mucosal immune system so as to provide a better ...
Jonathan E, Teitelbaum, W, Allan Walker
openaire   +2 more sources

Advances in Mucosal Immunity

Drugs, 1997
The mucosal immune system is the major interface between the host and the microbial environment and, given that role, it is not surprising that it contains the majority of the cells of the host immune system. The mucosal immune system is organised into inductive and effector sites.
openaire   +2 more sources

The mucosal immune system

Parasite Immunology, 2003
SUMMARYThis article outlines the lymphoid structures and cell types important in the intestinal immune response. Particular attention is paid to differences between rodents and man where there appears to be fundamental differences in the sources of the T and B cells which populate the mucosa.
openaire   +2 more sources

Innate Immunity in the Mucosal Immune System

Current Pharmaceutical Design, 2006
The mucosal immune system is equipped with unique innate and acquired defense mechanisms which provide a first line of protection against ingested and inhaled infectious agents. Peyer's patches (PPs) and nasopharynx-associated lymphoid tissue (NALT) have been shown to be important inductive sites for the initiation of the acquired phase of antigen ...
Tomonori, Nochi, Hiroshi, Kiyono
openaire   +2 more sources

Mucosal Immunization with DNA Vaccines

Microbes and Infection, 1999
The mucosal surface area of the gastrointestinal, genitourinary and respiratory tracts is more than 200 times greater than that of the skin and is the primary site of transmission of numerous diseases. The entry of pathogenic organisms at mucosal surfaces can be prevented by mucosal, but not systemic immunity.
M J, McCluskie, H L, Davis
openaire   +3 more sources

Mucosal Immunity in Allergic Rhinitis

Acta Oto-Laryngologica, 1993
Secretory IgA (SIgA) is the main agent protecting the mucosal districts against both infectious microorganisms and inert foreign macromolecules. A lack of secretory immunity has previously been described in patients with allergic rhinitis, but it is a controversial finding.
CORTESINA G   +5 more
openaire   +2 more sources

Stimulation of Mucosal Immunity

2003
The mucosal immune system is composed of distinct regional immune tissue (e.g., "GALT," gut-associated lymphoid tissue; "BALT," bronchus-associated lymphoid tissue; reproductive tract and breast tissue, and so forth) interconnected by trafficking of primed lymphocytes as a common "mucosa-associated lymphoid tissue," "MALT" (1).
Lewis, DJ, Hayward, CM
openaire   +5 more sources

Immunity at Mucosal Surfaces

Advances in Dental Research, 1996
The mucosae form a barrier between our bodies and a hostile external environment. Diseases and extrinsic factors which impair mucosal function may lead to serious consequences. The mucosal immune system is the primary mediator of specific immunity at mucosal surfaces.
openaire   +2 more sources

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