Post-pandemic upsurge of group A streptococcus infections: potential link to impaired herd trained immunity following COVID-19 lockdowns. [PDF]
Marcinkiewicz J.
europepmc +1 more source
Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner +6 more
wiley +1 more source
Trained immunity: induction of an inflammatory memory in disease. [PDF]
Schlüter T +4 more
europepmc +1 more source
Anthrax toxins inhibit immune cell chemotaxis by perturbing chemokine receptor signalling
Silvia Rossi Paccani +6 more
openalex +2 more sources
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source
Rubella immunization policy in Japan: Immunity gaps arising from program differences and inconsistent cutoff standards. [PDF]
Yoshika M.
europepmc +1 more source
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp +13 more
wiley +1 more source
Reconsidering rebound malaria: Zanzibari voices on acquired immunity, risk, and history. [PDF]
Graboyes M +3 more
europepmc +1 more source
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima +4 more
wiley +1 more source
Comment on: A single dose recombinant AAV based CHIKV vaccine elicits robust and durable protective antibody responses in mice. [PDF]
Xu S +8 more
europepmc +1 more source

