Results 71 to 80 of about 1,117,142 (241)

Passive Immunization against HIV/AIDS by Antibody Gene Transfer

Viruses, 2014
Despite tremendous efforts over the course of many years, the quest for an effective HIV vaccine by the classical method of active immunization remains largely elusive. However, two recent studies in mice and macaques have now demonstrated a new strategy
Lili Yang, Pin Wang
doaj   +1 more source

Immunity induced by valine-glycine repeat protein G imparts histoprotection of vital body organs against Acinetobacter baumannii

Journal of Genetic Engineering and Biotechnology, 2022
Background Efforts toward the development of an effective vaccine against Acinetobacter baumannii, one of the most notorious nosocomial pathogens, are still ongoing. In this regard, virulence factors are interesting targets.
Saeed Alipouri, Iraj Rasooli, Mohammad Hossein Ghaini, Abolfazl Jahangiri, Shakiba Darvish Alipour Astaneh, Fatemeh Ramezanalizadeh   +5 more
doaj   +1 more source

Nanobody–chlorin e6 conjugate for Nectin‐4‐mediated tumor targeting and enhanced photodynamic therapy

VIEW, EarlyView.
Nectin‐4 is frequently overexpressed in solid tumors, yet many PDT photosensitizers show poor water solubility and nonspecific uptake. A Nectin‐4‐targeted nanobody–chlorin e6 conjugate (NPC) improves aqueous solubility and selectively accumulates in Nectin‐4‐positive tumor cells.
Haodian Wan, Tao Ye, Yawei Bi, Jiayu Zhang, Wei Wu, Aochi Liu, Li Sun, Jie Lin, Ningli Chai, Manjie Zhang, Jian Ma   +10 more
wiley   +1 more source

The situations and strategies of amyloid⁃β⁃directed passive immunotherapy for Alzheimer's disease

Chinese Journal of Contemporary Neurology and Neurosurgery, 2019
It is widely believed that amyloid β⁃protein (Aβ) plays a core role in the pathogenesis of Alzheimer's disease (AD). Thus A β is one of main targets in the therapeutic explorations for AD.
Ya LI, An⁃ni ZHANG, Xu⁃ling WU, Yan ZHAO, Gang CAI, Dian HE   +5 more
doaj  

Passive antibody therapy in COVID-19

Nature reviews. Immunology, 2020
For over a century, transfusion of convalescent plasma from recovered individuals has been tried as a therapeutic approach when a novel pathogen emerges.
J. Abraham
semanticscholar   +1 more source

Allergic Sensitization to Inhalant Allergens in the Upper Respiratory Tract—the B Cell Side

Allergy, EarlyView.
ABSTRACT Allergic diseases are on the rise worldwide, driven by respiratory epithelial barrier dysfunction that promotes sensitization to inhalant allergens such as pollen, dust mites, pet dander, and fungal spores. These antigens trigger IgE‐mediated immune responses that lead to diseases such as allergic rhinitis (AR) and asthma.
Ola Grimsholm, Mohammed Zghaebi, Bita Hambrecht, Tanja Kalic, Christopher C. Udoye, Rudolf Manz, Barbara Bohle, Katarzyna M. Sitnik, Julia Eckl‐Dorna, Heimo Breiteneder   +9 more
wiley   +1 more source

Hen egg yolk antibodies (IgY), production and use for passive immunization against bacterial enteric infections in chicken: a review [PDF]

Biotechnologie, Agronomie, Société et Environnement, 2009
Enteric infections caused by Salmonella remain a major public health burden worldwide. Poultry, particularly chickens, are known to be the main reservoir for this zoonotic pathogen.
Chalghoumi R., Beckers Y., Portetelle D., Théwis A.   +3 more
doaj  

Passive immunization with influenza haemagglutinin specific monoclonal antibodies

Human Vaccines & Immunotherapeutics, 2018
The isolation of broadly neutralising antibodies against the influenza haemagglutinin has spurred investigation into their clinical potential, and has led to advances in influenza virus biology and universal influenza vaccine development.
Rajeev Rudraraju, Kanta Subbarao
doaj   +1 more source

A Case for Anti‐IgE Vaccination

Allergy, EarlyView.
ABSTRACT Immunoglobulin E (IgE) plays a central role in allergic diseases by binding to the high‐affinity receptor FcεRI on mast cells and basophils, where allergen‐induced crosslinking triggers potent inflammatory responses. Various mechanisms by which IgE responses are generated and functionally regulated remain elusive despite many years of research.
Paul Engeroff, Zahra Gharailoo, Monique Vogel, Martin F. Bachmann   +3 more
wiley   +1 more source

Preferential Presentation of High-Affinity Immune Complexes in Germinal Centers Can Explain How Passive Immunization Improves the Humoral Response

Cell Reports, 2019
Summary: Passive immunization (PI) with external antibodies has been used classically for rapid but temporary alleviation of disease. Transcending this role, recent studies have shown PI to induce lasting improvements in natural antibody production ...
Amar K. Garg, Rajat Desikan, Narendra M. Dixit   +2 more
doaj   +1 more source