A New Strategy Toward B Cell-Based Cancer Vaccines by Active Immunization With Mimotopes of Immune Checkpoint Inhibitors [PDF]
Frontiers in Immunology, 2020 Therapeutic monoclonal antibodies (mAbs), targeting tumor antigens, or immune checkpoints, have demonstrated a remarkable anti-tumor effect against various malignancies.
Joshua Tobias +16 more
doaj +4 more sources
A juvenile mouse model of anti-N-methyl-D-aspartate receptor encephalitis by active immunization [PDF]
Frontiers in Molecular Neuroscience, 2023 IntroductionAnti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a common autoimmune encephalitis, and it is associated with psychosis, dyskinesia, and seizures.
Shuyu He +17 more
doaj +2 more sources
Optimizing animal models of autoimmune encephalitis using active immunization [PDF]
Frontiers in Immunology, 2023 Background and objectivesEncephalitis is a devastating neurologic disorder with high morbidity and mortality. Autoimmune causes are roughly as common as infectious ones.
Jenny Linnoila +11 more
doaj +2 more sources
Protective Effects against the Development of Alzheimer’s Disease in an Animal Model through Active Immunization with Methionine-Sulfoxide Rich Protein Antigen [PDF]
Antioxidants, 2022 The brain during Alzheimer’s disease (AD) is under severe oxidative attack by reactive oxygen species that may lead to methionine oxidation. Oxidation of the sole methionine (Met35) of beta-amyloid (Aβ), and possibly methionine residues of other ...
Adam S. Smith +4 more
doaj +2 more sources
Progress in the preparation of an active immunization model of anti-N-methyl-D-aspartate receptor encephalitis in animals [PDF]
Frontiers in ImmunologyAnti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is the most common form of autoimmune encephalitis, and its primary immunologic mechanism is that NMDA antibodies bind to the NMDA receptor, causing NMDAR to internalize and weaken to trigger ...
Kuikui Zeng +3 more
doaj +2 more sources
Live Birth Rates after Active Immunization with Partner Lymphocytes [PDF]
Biomedicines, 2021 Although many potential causes have been established for recurrent implantation failure (RIF) and recurrent miscarriage (RM), about 50% of these remain idiopathic. Scientific research is focused on immunological risk factors. In the present study, we aim
Veronika Günther +6 more
doaj +2 more sources
ACTIVE IMMUNIZATION AGAINST POLIOMYELITIS [PDF]
Journal of Experimental Medicine, 1932 1. A single intracutaneous inoculation with a subinfective dose of the virus of poliomyelitis produces considerable immunity. 2. Virus-serum combinations produce an appreciable immunity, providing just sufficient serum is used to protect the animal from paralysis.
Maurice Brodie
exaly +5 more sources
Effect of active immunization with recombinant-derived goose INH-α, AMH, and PRL fusion protein on broodiness onset and egg production in geese (Anser cygnoides) [PDF]
Poultry Science, 2021 : This study was conducted to investigate the potential effects of active immunization against recombinant-derived goose inhibin-α (INH-α), anti-Müllerian hormone (AMH), and prolactin (PRL) fusion protein on broodiness onset and egg production in geese ...
Y. Zhang +6 more
doaj +2 more sources
Frontiers in Public Health, 2023 IntroductionDetection of community respiratory syncytial virus (RSV) infections informs the timing of immunoprophylaxis programs and hospital preparedness for surging pediatric volumes. In many jurisdictions, this relies upon RSV clinical test positivity
Elisabeth Mercier +20 more
doaj +1 more source
Immune suppression and immune activation in depression [PDF]
Brain, Behavior, and Immunity, 2011 Depression has been characterized as a disorder of both immune suppression and immune activation. Markers of impaired cellular immunity (decreased natural killer cell cytotoxicity) and inflammation (elevated IL-6, TNFα, and CRP) have been associated with depression.
Joshua, Blume +2 more
openaire +2 more sources