Results 131 to 140 of about 121,206 (265)

Muscle‐Specific Kinase Signaling and Its Therapeutic Potential

open access: yesMuscle &Nerve, EarlyView.
ABSTRACT The function of the neuromuscular junction (NMJ) is compromised in many neuromuscular diseases (NMDs) such as autoimmune or congenital myasthenia gravis (MG), amyotrophic lateral sclerosis (ALS), spinal muscular atrophy (SMA), and muscular dystrophies.
Stine Marie Jensen   +2 more
wiley   +1 more source

Determinants and gaps influencing zero-dose immunization and maternal Health service utilization in Nigeria: a cross-sectional household survey across six Nigerian states. [PDF]

open access: yesGlob Health Action
Akinjeji A   +8 more
europepmc   +1 more source

Disrupted joint clock is associated with rhythmic expression of bone destruction factors in collagen‐induced arthritis

open access: yesRheumatology &Autoimmunity, EarlyView.
Schematic Summary of Circadian Dysregulation in Arthritic Joints. This graphical abstract illustrates the key circadian disruptions observed in the collagen‑induced arthritis (CIA) model. The diagram depicts three main findings: (1) Nocturnal elevations in pro‑inflammatory cytokines (TNF‑α, IL‑6, IL‑17, IL‑1β, MIF) and bone‑destructive factors (DKK‑1 ...
Xiaogang Zhang   +7 more
wiley   +1 more source

Assessment of current colostrum feeding practices and passive transfer of immunity in dairy herds in Great Britain: A cross‐sectional study

open access: yesVeterinary Record, EarlyView.
Abstract Background Updated targets for measuring transfer of passive immunity (TPI) at the herd level have been suggested, but the current performance of dairy herds in Great Britain is unknown. Methods A cross‐sectional study was performed. Serum total protein (STP) data collected between October 2022 and October 2023 by 21 veterinary practices were ...
George Lindley   +3 more
wiley   +1 more source

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

open access: yesVIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf   +5 more
wiley   +1 more source

Microarrayed Allergen Molecules Distinguish IgE Sensitisation to Blomia tropicalis and Dermatophagoides pteronyssinus

open access: yesAllergy, EarlyView.
This study established a microarray containing a representative panel of purified Blo t and Der p allergens for the identification of patients sensitised to Blo t and/or Der p. Results indicate that the microarray based on Blo t and Der p allergens is a useful tool for the identification of Blo t‐ and/or Der p‐sensitised patients. The microarray may be
Nishelle Dsouza   +16 more
wiley   +1 more source

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