Results 121 to 130 of about 658,898 (341)

Parametric Immunization in Bond Portfolio Management [PDF]

, 2012
In this paper, we evaluate the relative immunization performance of the multifactor parametric interest rate risk model based on the Nelson-Siegel-Svensson specification of the yield curve with that of standard benchmark investment strategies, using ...
Bravo, Jorge, Fonseca, José
core  

Advanced Human Immune Cell‐Organoid Co‐Cultures for Functional Testing of Cancer Nanovaccines

Advanced Science, EarlyView.
Pancreatic ductal adenocarcinoma remains difficult to treat. We establish an organoid–immune co‐culture using patient‐derived organoids and matched T‐cells to assess cancer vaccines. A mesothelin‐targeted nanovaccine activates antigen‐specific T‐cells, increases IFN‐γ, and targets MSLN+ organoids.
Nathalia Ferreira, David Agorku, Andre Rosa, Julia Roosz, Lena Christ, Nicole Anderle, Ajinkya Kulkarni, Abir Hussein, Sana S. Sayedipour, Omar F. Luna, Tobias Legler, Philipp Ströbel, Fernando Albericio, Luis Cruz, Phillipp Beckhove, Peter Loskill, Frauke Alves, M. Andrea Markus, Fernanda Ramos‐Gomes   +18 more
wiley   +1 more source

Immunogenicity and safety study of 23-valent pneumococcal polysaccharide vaccine revaccination among elderly individuals aged 60–70 years in Shanghai, China

Frontiers in Immunology
BackgroundTo understand the immunogenicity and safety of the 23-valent pneumococcal polysaccharide vaccine in elderly individuals aged 60–70 years in Shanghai after revaccination.MethodsA total of 330 elderly people aged 60–70 years were recruited to ...
Jing Qiu, Zhi Li, Fang Huang, Zhuoying Huang, Xiufang Liang, Juan Li, Yuting Liao, Xiang Guo, Xiaodong Sun   +8 more
doaj   +1 more source

Experimental immunization of rats with a Streptococcus mutans 59-kilodalton glucan-binding protein protects against dental caries [PDF]

, 1996
Daniel J. Smith, Martin A. Taubman
openalex   +1 more source

Magnesium Structure‐Function Integration Platform for Spatiotemporal Multi‐Modality Therapy: Combining Hormonotherapy and Immunotherapy in Prostate Cancer

Advanced Science, EarlyView.
The schematic illustration of the MHSCG platform for spatiotemporal responsive GRb1 release to induce androgen deprivation therapy (ADT) and immunogenic cell death (ICD) multimodal therapy in prostate cancer. Abstract Metal‐based immunotherapy represents a promising strategy for enhancing antitumor efficacy; however, its clinical application is limited
Rui Zan, Qianping Mao, Keyi Wang, Guodong Zou, Shi Yang, Hua Qiu, Xiang Fang, Guiqing Wang, Xinyi Zhou, Jiexia Wen, Shuai Jiang, Ran Huang, Qiuming Peng, Tao Suo   +13 more
wiley   +1 more source

Immunization status and factors influencing hepatitis B vaccination of preterm infants in three provinces of China, 2019 to 2021

BMC Infectious Diseases
Background Premature infants have less physiologic reserve and often delayed vaccination compared to full-term infants. The birth dose of hepatitis B vaccine (HepB-BD) is an essential measure to achieve the goal of "zero infections" of hepatitis B virus ...
Li-fang Huang, Ao-di Huang, Xue Zhang, Lin Tang, Jing An, Jun Li, Hui Zheng, Zun-dong Yin, Fu-zhen Wang   +8 more
doaj   +1 more source

Human papillomavirus vaccination at age 9 or 10 years to increase coverage – a narrative review of the literature, United States 2014–2024

Human Vaccines & Immunotherapeutics
The Advisory Committee on Immunization Practices recommends routine human papillomavirus (HPV) vaccination at 11–12 years; the series can begin at age 9. U.S. HPV vaccination coverage is lower than other adolescent vaccinations.
Sarah K. Brewer, Ruth Stefanos, Neil C. Murthy, Amimah F. Asif, Shannon Stokley, Lauri E. Markowitz   +5 more
doaj   +1 more source

Empirical Research on the Demand for Influenza Vaccination Among the Elderly, [PDF]

Purpose: This paper analyses what factors determine the demand for vaccination among the elderly as a high risk group. Using the estimation results, this paper then evaluates how legal requirements and/or subsidies affect their demand.
Yasushi Ohkusa
core  

Evaluation of a human diploid cell strain rabies vaccine: final report of a three year study of pre-exposure immunization [PDF]

, 1982
G. S. Turner, Karl G. Nicholson, D. A. J. Tyrrell, F. Y. Aoki   +3 more
openalex   +1 more source

Soft‐Drug‐Inspired MnSTF Nano‐Adjuvant for Safe and Synergistic cGAS–STING Activation in Tumor Immunotherapy

Advanced Science, EarlyView.
This study introduces MnSTF, a soft‐drug‐inspired nanoadjuvant that overcomes the systemic toxicity of STING agonists. Through Mn2+ coordination with an ENPP1 inhibitor, it enables safe cGAS‐STING activation, remodels the tumor immune microenvironment, and synergizes with radiotherapy or vaccines to elicit robust antitumor immunity.
Guangfei Sun, Jiancheng Pan, Rui Li, Ruoxi Li, Ziyan Liu, Jinhui Wu, Tingsheng Lin, Yiqiao Hu, Ahu Yuan   +8 more
wiley   +1 more source