Results 271 to 280 of about 662,606 (363)

Pneumococcal membrane particles promote serotype-independent cellular and humoral immunity and protect against pneumococcal colonization. [PDF]

open access: yesProc Natl Acad Sci U S A
Dookie R   +11 more
europepmc   +1 more source

Diagnostic antibodies at an inflection point: From discovery platforms to design‐oriented engineering

open access: yesVIEW, EarlyView.
This study systematically organizes the evolution of diagnostic antibodies from discovery platforms to design‐oriented engineering and analyzes the strengths and limitations of each approach. Meanwhile, it provides a critical, literature‐driven synthesis of current challenges, proposing integrated strategies for assay‐aware and function‐driven antibody
Qitao Song   +14 more
wiley   +1 more source

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

open access: yesVIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf   +5 more
wiley   +1 more source

Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

open access: yesVIEW, EarlyView.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source

Prevalence of Eight Viruses in Captive Amur Tigers (Panthera tigris altaica) From Harbin, China 中国哈尔滨市圈养东北虎8种病毒的流行

open access: yesWildlife Letters, EarlyView.
The Amur tiger, an endangered flagship species mainly found in the Russia Far East and Northeastern China, holds immense biological importance, and has been listed under the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES).
Wei Xie   +15 more
wiley   +1 more source

Evaluating respiratory syncytial virus immunization strategies for infants in Canada: A cost-utility analysis. [PDF]

open access: yesPLoS One
Gebretekle GB   +15 more
europepmc   +1 more source

Crisis micro‐learning: A framework for understanding the micro‐flow of policy learning and Australia's COVID‐19 response

open access: yesAustralian Journal of Public Administration, EarlyView.
Abstract COVID‐19 has intensified interest in crisis policy learning, yet the micro‐level interactions among political, bureaucratic, and expert actors remain underexplored. We conceptualise an ideal‐type framework for the micro‐flow of crisis learning, an ordinarily epistemic and context‐specific process of individual‐level interactions, where lessons
Neil Mortimer, Nicholas Bromfield
wiley   +1 more source

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