Results 101 to 110 of about 2,173,693 (307)
Overcoming Drug Resistance by Paclitaxel Resistance in Triple‐Negative Breast Cancer
Advanced Science, EarlyView.In the murine triple‐negative breast cancer (TNBC) model, chemotherapy effectively increases tumor neoantigen burden (TNB). Here, the study constructs a liposomal nanovaccine using antigens derived from in vitro chemotherapy‐treated paclitaxel‐resistant TNBC 4T1 cells.
Bo Chen +10 more
wiley +1 more source
Typhoid Immunization : Recommendations of the Advisory Committee on Immunization Practices (ACIP) [PDF]
"These revised recommendations of the Advisory Committee on Immunization Practices update previous recommendations (MMWR 1990;39[RR-10]:1-5). They include information on the Vi capsular polysaccharide (ViCPS) vaccine, which was not available when the ...
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Advanced Science, EarlyView.ABSTRACT Memory T cells exhibit long‐term persistence, a defining feature that underpins durable clinical responses to adoptive immunotherapies. The mechanisms that integrate metabolic cues with transcriptional control of memory fate remain undetermined. Here, we identify HS1‐binding protein 3 (HS1BP3) is preferentially expressed in memory CD8+ T cells.
Siyang Wang +13 more
wiley +1 more source
Advanced Science, EarlyView.Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang +10 more
wiley +1 more source
Three papers on influenza immunization presented at the 14th Immunization Conference, 1979, and at the 15th Immunization Conference, 2000.The Federally supported Influenza Immunization Program was developed through a vigorous scientific and public review
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Immunization schedules : schedule changes & guidance [PDF]
The COVID-19 pandemic is changing rapidly and requires different strategies to maintain clinical preventive services, including immunization. Find up-to-date guidance on childhood, adult, and maternalexternal icon vaccination and clinical practice ...
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The Pan African Medical Journal, 2018 While paper-based immunization registries are the prevalent form of documenting individual-level immunization service delivery in Africa, some countries are interested in transitioning to electronic immunization registries (EIRs) which have the potential
Apophia Namageyo-Funa +3 more
doaj +1 more source
Advanced Science, EarlyView.Cryo‐electron microscopy structures reveal two distinct neutralization mechanisms of fully human monoclonal antibodies targeting the Shiga toxin 1a B subunit. RDS059 occludes the Gb3 receptor‐binding site, whereas RDS045 engages a lateral quaternary epitope to disrupt holotoxin assembly.
Jianting Ke +10 more
wiley +1 more source
Financing of immunization programs
, 2023 Abstract Ensuring adequate funding to immunize all newborn children every year with the vaccines in the national schedule and new vaccines to be introduced requires considerable resources. This chapter provides an overview of the ways in which countries are currently financing both the vaccine and delivery components of their ...
openaire +1 more source
Advanced Science, EarlyView.AI‑guided single‑cell transcriptomics identifies OGT as a key regulator enriched in rheumatoid arthritis fibroblast‑like synoviocytes (RA‐FLSs). Inflammatory stimuli activate the OGT–SAP130 axis, which modulates the H3K27ac/H3K27me3 balance and epigenetically silences BTG2, promoting aggressive transformation of RA‑FLSs.
Duoli Xie +14 more
wiley +1 more source