Results 241 to 250 of about 6,251,756 (328)
Efficacy of House Dust Mite Immunotherapy in Chinese Allergic Rhinitis Patients With Diverse Sensitization Patterns: A Multicenter Study (COVER Study)
Allergy, EarlyView.This prospective multicenter study corroborates the efficacy of AIT with the native HDM allergen extract in Chinese AR patients with diverse HDM sensitization patterns. HDM sensitization pattern affects the efficacy of AIT, with patients sensitized to both major and minor allergens of HDM showing improved outcomes with HDM SCIT.Qingxiu Xu, Xuan Yuan, Wang Liao, Hao Chen, Qing Jiang, Lin Yang, Jin Liu, Le Li, Nan Huang, Wenjing Li, Yaqi Yang, Dongxia Ma, Jun Bai, Zhihai Xie, Rongfei Zhu +14 morewiley +1 more sourceActive Surveillance for Myocarditis and Pericarditis in Canadian Children from 2021 to 2022: A Canadian Immunization Monitoring Program ACTive Study
Karina A. Top, Julie A. Bettinger, Joanne E. Embree, Taj Jadavji, Rupeena Purewal, Laura Sauvé, Jesse Papenburg, Shelley L. Deeks, Sarah E. Wilson, Nagib Dahdah, Manish Sadarangani, Scott A. Halperin, Fatima Kakkar, Shaun K. Morris, Natalie Bridger, Jeannette Comeau, Roseline Thibeault, Marc Lebel, Nicole Le Saux, Kescha Kazmi, Jeffrey M. Pernica, Jared Bullard, Rupesh Chawla, Cora Constantinescu, Catherine Burton +24 moreopenalex +2 more sourcesThe Therapeutic Potential of Farm Dust Extracts in a Mouse Model of Eosinophilic Inflammation
Allergy, EarlyView.Farm dust extract (FDE) treatment reduces airway eosinophilia, mucus overproduction, and MHC‐II expression on DCs, limiting antigen presentation and Th2 inflammation. It increases PD‐L1 on DCs, promoting T cell deactivation. Additionally, FDE enhances Tregs and upregulates CTLA‐4, reinforcing suppression.Rabia Ülkü Korkmaz, Jimmy Omony, Xiaomei Tan, Markus Klotz, Guilherme Dragunas, Sirui Chen, Soni Shankhwar, Zeynep Ertüz, Christoph Müller, Mohab Ragab, Aicha Jeridi, Romina Augustin, Janna Nawroth, Theodore S. Kapellos, Bettina Rankl, Ali Önder Yildirim, Erika von Mutius +16 morewiley +1 more sourceFirst Field Test of the Novel Integration Mapping Tool for COVID-19 Vaccination Integration into National Immunization Programs and Primary Healthcare - A Case Study from Cote d'Ivoire
, 2023 Amani A, Ekra Kouadio D, Brou G, Yao K, Aka Lépri N, Kouakou E, Kouadio SK, Gahongano G, Gadiry Fadiga A, Aziz Gbaya A, Efe-Aluta O, MBOUSSOU FFR, Mirza I, Schreiber B. +13 moreeuropepmc +1 more sourceMajor Cat Allergen Fel d 4: Structure and Identification of a Cross‐Reactive IgE‐Epitope‐Containing Area
Allergy, EarlyView.This study reports the three‐dimensional structure of an important cat allergen, Fel d 4, that shares high homology with Equ c 1 (i.e., major horse allergen) and Can f 6 (i.e., dog allergen).
The C‐terminal region of the Fel d 4 contains a major IgE‐reactive epitope.Nikolina Todorović, Daria Trifonova, Zicheng Liu, Mirela Curin, Laszlo Schooltink, Theo Sagmeister, Christoph Grininger, Renata Kiss, Nina Gottstein, Bernd Gesslbauer, Andreas Winkler, Tea Pavkov‐Keller, Alexander Karaulov, Rudolf Valenta, Walter Keller +14 morewiley +1 more sourceLong‐Term Efficacy and Safety of Ligelizumab as Re‐Treatment in Patients With Chronic Spontaneous Urticaria
Allergy, EarlyView.Ligelizumab re‐treatment in CSU patients showed sustained efficacy and tolerability. Over 50% achieved symptom control (UAS7 ≤ 6) by Week 12; benefits maintained through Week 52. No new safety signals observed; aligns with prior PEARL trial outcomes. CSU, chronic spontaneous urticaria; mg, milligram; q4w, every 4 weeks; UAS, urticaria activity score ...Ana M. Gimenez‐Arnau, Marcus Maurer, Adam Reich, Chia‐Yu Chu, Diana Deleanu, Gordon Sussman, Jorge Sanchez, Knut Brockow, Koremasa Hayama, Michihiro Hide, Mohamed Denguezli, Raisa Meshkova, Roberta F. J. Criado, Sarbjit Saini, Solange Valle, Eva Hua, Pengpeng Wang, Alis Burciu, Isabelle Indermuehle, Vineeth Varanasi, Yolandi Joubert, Thomas Severin, Manmath Patekar +22 morewiley +1 more source
