Results 231 to 240 of about 2,173,693 (307)

First Field Test of the Novel Integration Mapping Tool for COVID-19 Vaccination Integration into National Immunization Programs and Primary Healthcare - A Case Study from Cote d'Ivoire

open access: yes, 2023
Amani A   +13 more
europepmc   +1 more source

Enterovirus infections in children

open access: yesPediatric Investigation, EarlyView.
Enteroviruses (EVs) are major pathogens causing a wide spectrum of diseases in children worldwide. This review summarizes the epidemiology, virology, viral replication, and virus‐host interactions of EVs. It also highlights current advances in clinical diagnosis, antiviral therapies, and vaccine development, providing insights into future strategies ...
Xiangpeng Chen   +11 more
wiley   +1 more source

Natural Polysaccharides for Rheumatoid Arthritis Therapy: Mechanism, Drug Delivery and Clinical Application

open access: yesPhytotherapy Research, EarlyView.
Schematic overview of the experimental models, therapeutic mechanisms, drug delivery systems, and clinical potential of natural polysaccharides in rheumatoid arthritis. ABSTRACT Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized primarily by chronic synovitis.
Luxin Li   +14 more
wiley   +1 more source

Disrupted joint clock is associated with rhythmic expression of bone destruction factors in collagen‐induced arthritis

open access: yesRheumatology &Autoimmunity, EarlyView.
Schematic Summary of Circadian Dysregulation in Arthritic Joints. This graphical abstract illustrates the key circadian disruptions observed in the collagen‑induced arthritis (CIA) model. The diagram depicts three main findings: (1) Nocturnal elevations in pro‑inflammatory cytokines (TNF‑α, IL‑6, IL‑17, IL‑1β, MIF) and bone‑destructive factors (DKK‑1 ...
Xiaogang Zhang   +7 more
wiley   +1 more source

Infection risk in rheumatoid arthritis patients treated with biologic and targeted therapies

open access: yesRheumatology &Autoimmunity, EarlyView.
In this context, infections associated with each biologic and targeted drug are summarized to inform the stratification of RA patients, including the characteristics of the susceptible patients and their concomitant therapy. We aim to provide a benefit‐risk analysis for clinical decision, and vital indications for the prevention of highly correlated ...
Lujing Wang, Jieshi Lin, Jie Qian
wiley   +1 more source

Predicting Life Expectancy in Upper‐Middle‐Income Countries Using Machine Learning: A Comparative Analysis

open access: yesSustainable Development, EarlyView.
ABSTRACT This study aims to estimate life expectancy in upper‐middle‐income countries using socio‐economic and health‐related variables obtained from the World Bank's World Development Indicators database. To this end, four machine learning algorithms—Support Vector Regression (SVR), Random Forest, Gradient Boosting, and XGBoost—were applied; the ...
Esra Süzen, Mehmet Kayakuş
wiley   +1 more source

Ethnic Diversity and Child Health: New Insights From Ghana

open access: yesSustainable Development, EarlyView.
ABSTRACT This study examines the impact of ethnic diversity on child health in Ghana using nationally representative panel data. We assess whether greater community‐level ethnic heterogeneity is associated with poorer child health outcomes and explore poverty and access to prenatal care as potential mechanisms.
Opoku Adabor
wiley   +1 more source

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