Results 231 to 240 of about 68,916 (303)

CLINICO–Demographic Profile and Outcomes of Hospitalised Children With Diphtheria in A Tertiary Care Hospital of Peshawar

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim To determine the clinico‐demographic profile and predictors of mortality in hospitalised children with diphtheria. Methods This retrospective cohort study included 202 children aged 5–16 years diagnosed with diphtheria per WHO criteria at Lady Reading Hospital, Peshawar, from January 2023 to December 2024. Data on demographics, vaccination
Amir Muhammad   +6 more
wiley   +1 more source

Socioeconomic Risk Factors for Incomplete Vaccination in Swedish Two‐Year‐Olds—A Nationwide, Population‐Based Cohort Study

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim To analyse the association between specific socioeconomic measures and the risk of incomplete vaccination for diphtheria‐tetanus‐pertussis (DTP) and measles‐containing vaccine (MCV) in Swedish two‐year‐olds. Methods This nationwide, population‐based cohort study included 227 457 children born in Sweden during 2014–2015.
Cecilia Chrapkowska Almqvist   +5 more
wiley   +1 more source

Structured Antenatal Counselling Improves Maternal Influenza and Pertussis Uptake: A Prospective Comparative Study in Greece

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim Maternal immunization is essential for preventing severe influenza and pertussis in pregnant women and young infants. Despite clear recommendations, uptake in Greece remains suboptimal, and evidence on effective antenatal interventions is limited.
A. Drougia   +7 more
wiley   +1 more source

Brokers, Collaborators and Knowledge Translators: Expanding the Role of Research Assistants in Geographic Research

open access: yesAsia Pacific Viewpoint, EarlyView.
ABSTRACT While ‘local’ research assistants (RA) often play a key role in knowledge production in fieldwork‐based disciplines like geography, their role and agency often remain silenced. This paper brings together scholarship in feminist geography and critical development studies to reposition RAs as brokers, collaborators, and knowledge translators.
Zali Fung
wiley   +1 more source

Perspectives on Pertussis Prevention

open access: yes
Acta Paediatrica, EarlyView.
Ulrich Heininger
wiley   +1 more source

Cardiovascular toxicity from immune checkpoint inhibitor therapy: an inflammatory continuum

open access: yesBritish Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitor (ICI) therapy has markedly improved outcomes in advanced malignancies but has also revealed a distinct spectrum of cardiovascular immune‐related adverse events. Myocarditis represents the most severe manifestation, while non‐inflammatory left ventricular dysfunction and vascular inflammation have emerged as additional ...
Fabrice Reyes   +7 more
wiley   +1 more source

Multivalent antibody‐based conjugates as new tools for tailored modulation of G protein–coupled receptors

open access: yesBritish Journal of Pharmacology, EarlyView.
The G protein–coupled receptor (GPCR) superfamily consists of the most common targets of approved drugs. Targeting GPCRs offers appealing avenues for therapeutic development. Antibodies and their fragments, such as single‐domain antibodies (VHHs or nanobodies), have emerged as useful alternatives to small molecule pharmacophores as building blocks in ...
Shivani Sachdev, Ross W. Cheloha
wiley   +1 more source

Refining the treatment of immune checkpoint inhibitor–associated myocarditis: Challenges, innovations and rechallenge considerations

open access: yesBritish Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitor (ICI)‐associated myocarditis has emerged as a severe and clinically complex immune‐related toxicity that poses significant challenges for therapeutic decision‐making in routine cardio‐oncological care. High‐dose corticosteroids remain the first‐line therapy, yet their timing, dosage and tapering require careful clinical ...
Raluca I. Mincu   +10 more
wiley   +1 more source

Worldwide Impact of Human Development and Inequality on the Prevalence of Asthma, Rhinoconjunctivitis and Eczema. Global Asthma Network's Ecological Study

open access: yesClinical &Experimental Allergy, EarlyView.
Global Asthma Network Phase I surveyed children, adolescents, and adults worldwide to assess the prevalence of asthma, rhinoconjunctivitis, and eczema. Human Development Index (HDI) and Gini inequality index (GinI) were important explanatory factors for prevalence variability of these conditions, with hotspots in areas with high HDI and high GinI ...
Luis García‐Marcos   +15 more
wiley   +1 more source

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