Immunoadsorption and subsequent administration of intravenous immunoglobulin (IVIG) have shown beneficial effects on cardiac function and symptoms in patients with dilated cardiomyopathy. Biomarkers play an emerging role in disease monitoring and outcome
Mirjam Keßler +2 more
exaly +5 more sources
A one-year-old, female intact Samoyed, 12.5 kg, was presented with coughing for 2 weeks, progressive appendicular and axial muscle weakness, megaesophagus and labored breathing for 5 days. There was no improvement with standard treatment.
Florian Sänger +5 more
doaj +2 more sources
Efficacy and safety of acute-phase immunotherapy for adult autoimmune encephalitis: a systematic review and network meta-analysis [PDF]
BackgroundAutoimmune encephalitis (AE) is an immune-mediated inflammatory disorder of the central nervous system associated with substantial morbidity. Acute-phase immunotherapy is crucial for improving outcomes, yet the comparative efficacy and safety ...
Yan Deng +6 more
doaj +2 more sources
Intermittent immunoadsorption in critically ill patients with neuroimmunological disorders: a retrospective study [PDF]
ObjectivesThis study aimed to evaluate the efficacy and safety of intermittent immunoadsorption (IA) in critically ill patients with refractory autoimmune neurological disorders.MethodsWe retrospectively reviewed 13 patients admitted to the neurocritical
Qian Wu +5 more
doaj +2 more sources
Case report: anti-GAD65 antibody-associated epilepsy as the primary manifestation of chronic graft-versus-host disease [PDF]
Central nervous system involvement in chronic graft-versus-host disease (CNS-cGVHD) is rare. This case report describes a young man who developed anti-glutamic acid decarboxylase 65 (GAD65) antibody-associated epilepsy after undergoing matched sibling ...
Suge Yang +4 more
doaj +2 more sources
A robust and scalable immunoadsorbent platform based on the high-affinity M03-IgG antibody for targeted IL-6 Removal in cytokine storm [PDF]
The therapeutic removal of interleukin-6 (IL-6) via blood perfusion has demonstrated clinical efficacy in the management of autoimmune diseases and sepsis.
Yaxi Yang +13 more
doaj +2 more sources
Immunoadsorption and subsequent immunoglobulin G replacement (IA/IG) in patients with dilated cardiomyopathy: a systematic review and meta-analysis [PDF]
BackgroundDilated cardiomyopathy (DCM) is a refractory cardiac disease with significant morbidity and mortality. Although immune adsorption combined with immunoglobulin G replacement therapy (IA/IG) has shown potential in treating DCM, only small-scale ...
Xiao Xia +16 more
doaj +2 more sources
Immunoadsorption versus double-dose methylprednisolone in refractory multiple sclerosis relapses
Objective Intravenous methylprednisolone is the standard treatment for a multiple sclerosis relapse; however, this fails to improve symptoms in up to one quarter of patients.
Steffen Pfeuffer +12 more
doaj +1 more source
Extracorporeal Therapy in Dermatology
Extracorporeal therapy is a treatment modality where human blood undergoes favorable technical modifications and is reintroduced into the same patient.
Sumit Sen +2 more
doaj +1 more source
Analysis of nAChR Autoantibodies Against Extracellular Epitopes in MG Patients
Myasthenia gravis (MG) is an autoimmune disorder caused by autoantibodies targeting components of the postsynaptic membrane of the neuromuscular junction (NMJ), leading to neuromuscular transmission deficiency.
Maria Michail +6 more
doaj +1 more source

