Results 171 to 180 of about 6,254 (213)

Immunoadsorption in Lupus Myocarditis

Therapeutic Apheresis and Dialysis, 2004
Abstract:  Reduction of pathological autoantibodies may be useful in the treatment of systemic lupus erythematosus (SLE). On the other hand clinically manifested myocarditis in SLE, though uncommon, may be life‐threatening and its pathogenesis has been ascribed to autoimmunity.
Ioannis, Griveas, Aggelos, Sourgounis, Georgios, Visvardis, Ioannis, Zarifis, Parthena, Kyriklidou, Georgios, Sakellariou   +5 more
openaire   +2 more sources

Immunoadsorption for autoimmune encephalitis

Atherosclerosis Supplements, 2017
Autoimmune encephalitis is a severe inflammatory disorder of the brain. The discovery that several non-infectious forms of encephalitis are associated with autoantibodies was a breakthrough in the care of this previously untreatable group of patients. The correlation of antibody type and titer with pattern and severity of symptoms was essential for the
Cordula, Fassbender, Reinhard, Klingel, Wolfgang, Köhler   +2 more
openaire   +2 more sources

Immunoadsorption of factor VIII inhibitors

Current Opinion in Hematology, 2004
Extracorporeal immunoadsorption is being increasingly applied in a variety of disorders. This approach is particularly suited to removal of antibodies or inhibitors to coagulation factor VIII and may be particularly useful before the administration of large amounts of expensive replacement or bypass therapy for patients with hemophilia who are bleeding,
John, Freedman, M Bernadette, Garvey
openaire   +2 more sources

Immunoadsorption in the treatment of Acquired Haemophilia

Atherosclerosis Supplements, 2009
In acquired haemophilia (AH) healthy humans can suddenly develop severe bleeding due to autoantibodies (inhibitors) against clotting factors, especially factor VIII. The mortality rate of 21 % is considerable, and standardized treatment protocols have not been developed due to the low disease frequency (1-4 per million).
Heike, Zeitler, Gudrun, Ulrich-Merzenich, Darius, Panek, Georg, Goldmann, Natascha, Vidovic, Hans-Hermann, Brackmann, Johannes, Oldenburg   +6 more
openaire   +2 more sources

Depletion of NK by Cellular Immunoadsorption

The Journal of Immunology, 1979
Abstract The binding of human natural killer (NK) cells to their tumor cell targets was investigated by using monolayers of sensitive target cell lines. Monolayers of K562 and HSB, a myeloid and T cell line, respectively, were prepared on poly-L-lysine-coated plastic tissue culture dishes and briefly fixed with 0.2% formaldehyde. Freshly
P J, Jensen, H S, Koren
openaire   +2 more sources

Immunoadsorption for coagulation factor inhibitors

Transfusion, 1991
Inhibitors to coagulation factors are among the most difficult problems in the management of coagulation disorders. Most presently available therapy does not assure hemostasis. An extracorporeal immunoadsorption system, which selectively binds IgG, was used to lower inhibitor levels in eight patients on 10 occasions. In this system, separated plasma is
J, Uehlinger, G R, Button, J, McCarthy, A, Forster, R, Watt, L M, Aledort   +5 more
openaire   +2 more sources

Avidity in immunoadsorption of IgG antibodies

Immunochemistry, 1974
Abstract Fab (3·5 S ) fragments were derived from IgG fractions of anti-dinitrophenyl and anti-lysergil antisera by papain digestion to reduce avidity forces due to polyvalency. The Fab fractions were immunoadsorbed to obtain active purified fragments.
D E, Lopatin, E W, Voss
openaire   +2 more sources

Immunoadsorption therapy for paraneoplastic syndromes

Journal of Neuro-Oncology, 1998
Paraneoplastic neurologic syndromes associated with systemic cancer are being increasingly recognized. Although these syndromes are thought to be immunologically mediated treatment with steroids, immunoglobulin and plasmapharesis has been disappointing.
T T, Batchelor, M, Platten, F H, Hochberg   +2 more
openaire   +2 more sources

Immunoadsorption for systemic lupus erythematosus

Atherosclerosis Supplements, 2009
Immunoadsorption (IAS) with various methods is used as a rescue therapy in severely ill SLE patients who are refractory to conventional therapeutic procedures. The method aims at the rapid and extensive removal of pathogenic immunocomplexes (IC) and (auto-) antibodies (Abs).
G H, Stummvoll, U, Julius, K, Derfler, M, Aringer   +3 more
openaire   +2 more sources

Immunoadsorption in Multifocal Motor Neuropathy

Journla of Immunotherapy, 1999
To our knowledge, this is the first reported application of immunoadsorption in a patient with multifocal motor neuropathy (MMN). The diagnosis relied on the typical clinical features, markedly increased IgM-GM1 antibodies, multiple motor conduction blocks, and motor nerve biopsy.
J, Finsterer, K, Derfler
openaire   +2 more sources