Results 181 to 190 of about 6,254 (213)
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Purification of ornithine aminotransferase by immunoadsorption
Analytical Biochemistry, 1988Ornithine aminotransferase was purified by conventional biochemical methods from rat kidney, rat liver, and human liver. Affinity-purified antibodies raised to the rat kidney enzyme were used to produce an immunoadsorbent enabling a one-step purification of ornithine aminotransferase to be made from crude human liver extracts.
J M, Leah, E E, Billett, T, Palmer
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Removal of Pathogenic Autoantibodies by Immunoadsorption
Annals of the New York Academy of Sciences, 2005Autoimmune diseases result from disrupted tolerance to self-antigens and subsequent damage to tissues and organs. In several diseases, specific autoantibodies have been either proved or suspected to play a role in this process. Consequently, several strategies have been devised in an attempt to discard the destructive immunoglobulins.
Alon Y, Hershko, Yaakov, Naparstek
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Biocompatibility of extracorporeal immunoadsorption systems
Transfusion Science, 1990Following the first publication of a technique aiming for clinical application in 1969, extracorporeal immunoadsorption is increasingly finding a place among haemapheresis techniques. The apparent advantages outweigh the technical difficulties and economical drawbacks still connected with this treatment modality.
J G, Kadar, H, Borberg
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Immunoadsorption therapy and complement activation
Transfusion and Apheresis Science, 2005Complement activation was studied in six patients treated with immunoadsorption columns Ig-ADSOPAK for myasthenia gravis. Mean therapy duration was 18.6 months (range 4-28 months). Prior and after each procedure, concentrations of C3 and C4 were examined, hemolytic activity of complement by a classic pathway (CH50) was determined, as well as terminal ...
J, Pták, J, Lochman
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Immunoadsorption in Dilated Cardiomyopathy
2006Dilated cardiomyopathy (DCM) is characterized by progressive reduction in contractile function and by dilatation of the right and left ventricles. Abnormalities of the cellular and humoral immune system are present in patients with myocarditis and DCM. Several antibodies against cardiac structures have been detected in DCM patients.
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Immunoadsorption for connective tissue disease
Atherosclerosis Supplements, 2013Distinct connective tissue diseases (CTD's) such as systemic lupus erythematosus (SLE), systemic sclerosis, mixed connective tissue disease as well as dermato- and polymyositis comprise a group of diseases, where autoantibodies are not merely indicators of autoimmune disease, but also play an relevant role in the underlying pathogenicity.
B, Hohenstein +2 more
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Immunoadsorption therapy in dilated cardiomyopathy
Expert Review of Cardiovascular Therapy, 2014Dilated cardiomyopathy is a common myocardial disease characterized by ventricular chamber enlargement and systolic dysfunction that result in heart failure. In addition to genetic predisposition, viral infection and myocardial inflammation play a causal role in the disease process of dilated cardiomyopathy.
Stephan B, Felix +2 more
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Immunoadsorption in patients with dilated cardiomyopathy
Atherosclerosis Supplements, 2009Dilated cardiomyopathy (DCM) is characterized by ventricular enlargement and progressive systolic and diastolic dysfunction. Disturbances of the cellular and humoral immune system are frequently observed in DCM. Circulating antibodies of the IgG class against diverse myocardial antigens have been identified and are thought to play a causative role in ...
Lars R, Herda +2 more
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Immunoadsorption for the Treatment of Bullous Pemphigoid
Therapeutic Apheresis, 1997Abstract: We treated 2 intractable patients with pemphigoid by absorbent plasmapheresis using dextran sulfate conjugated cellulose columns with an automated regenerating unit. During a 2 week period, this plasmapheresis was performed 4 to 6 times for Cases 1 and 2, respectively.
N, Ino +4 more
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