Results 121 to 130 of about 333,804 (300)
Advanced Science, EarlyView.FGF13 is upregulated in DRG neurons of PIPNP model mice. DRG neuron‐specific knockout of FGF13 ameliorates PIPNP symptoms. Mechanistically, FGF13 potentiates microtubule detyrosination by promoting VASH1 binding to microtubules. FGF13 knockout suppresses VASH1‐mediated microtubule detyrosination and promotes α‐tubulin tyrosination.
Yiming Dong +10 more
wiley +1 more source
PROTEOMICS applied to NUTRIGENOMICS: 2DE and Immunoblotting
, 2018 Theoretical-pratical explanation of how 2DE and immunoblotting technology can be involved in the characterization of bioactive compounds of food ...
Cristina Lamberti
core
Buffer Recipes for quantitative immunoblotting - rinsing and blocking agents v1
, 2017 These are the recipes for blocking and rinsing agents for the quantitative immunoblotting protocol from the Campbell Lab.
Doug Campbell, Natalie Donaher
core +1 more source
Auto‐Downregulation of the Florigen FT Production Prevents Precocious Flowering in Plants
Advanced Science, EarlyView.This study shows that the leaf vein‐expressed FD complexes with the florigen FT to bind DNA motifs in FT promoter, which antagonizes CONSTANS‐mediated FT activation to feedback down‐regulate FT expression. This prevents an excessive induction of FT expression by inductive photoperiods, thereby precluding precocious transition to flowering in ...
Shu Tian, Xiao Luo, Bowen Cui, Yuehui He
wiley +1 more source
Analysis of iNOS protein levels in TNBC patients by immunoblotting.
, 2015 Analysis of iNOS protein levels in TNBC patients by immunoblotting.
Yiming Li (40290) +14 more
core +1 more source
Citation: 'immunoblot' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13276 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire +1 more source
Advanced Science, EarlyView.Our research unveiled a regulatory paradigm wherein TRIM25 orchestrates the ubiquitin‐mediated degradation of UGDH. UGDH modulates the protein stability of TJP1 by regulating O‐GlcNAcylation levels, effectively impeding the metastasis of ccRCC. Our insights elevate UGDH to a pivotal biomarker and tumor suppressor, marking the first demonstration that ...
Xiaolin Chen +13 more
wiley +1 more source
Immunoblotting analysis of surface-exposed proteins.
, 2014 (A) Five recombinant SEPs purified from E. coli cell lysate were separated by 12% SDS-PAGE and stained by G-250 Coomassie Brilliant Blue. (B) Immunoblotting analysis of SEPs: lane M, protein molecular mass markers; lanes 1 to 5, rTolC, rPorin_4, rAdr1 ...
Xiaolu Xiong (436303) +5 more
core +1 more source
Advanced Science, EarlyView.. ABSTRACT Neuroinflammation driven by microglial activation is a defining feature of Alzheimer's disease (AD), yet the molecular mechanisms sustaining this proinflammatory state remain unclear. Here, we identify the deubiquitinase OTUD7B as a critical regulator of microglial activation and AD pathology.
Luyao Li +15 more
wiley +1 more source