Results 181 to 190 of about 4,533 (248)
Immunocompetency or “Supposed Immunocompetency”? Is it an Absolute Term?
Actas Dermo-Sifiliográficasopenaire +1 more source
Australian Veterinary Journal, EarlyView.A 3‐year‐old male Border Collie diagnosed with immune‐mediated dermatopathy, managed with tapering prednisolone and cyclosporine, developed rapidly progressive ocular signs and additional cutaneous lesions. Histopathology, mycological culture, polymerase chain reaction and sequencing confirmed intraocular and cutaneous infection due to Curvularia ...
T Brasil‐Ervedosa +4 more
wiley +1 more source
British Journal of Haematology, EarlyView.Summary Immune dysfunction is implicated in the aetiology of Hodgkin lymphoma (HL), but the association between inborn errors of immunity (IEI) and HL remains poorly understood. We conducted a retrospective, register‐based case–control study in Sweden over five decades to investigate the relationship between IEI and HL. Individuals diagnosed with HL in
Agnes Winsa +7 more
wiley +1 more source
Pyomyositis in an immunocompetent man
Revista da Sociedade Brasileira de Medicina TropicalElcio Bakowski +4 more
openaire +3 more sources
Cancer Science, EarlyView.Nestin‐driven green fluorescent protein (ND‐GFP) expressing peripheral blood vessels and nerves in the subcutaneous tissue of the ND‐GFP mice extended into the transplanted melanoma such that ND‐GFP was enhanced at the margin of the melanoma compared to the tumor‐free side.
Koya Obara +8 more
wiley +1 more source
Daraxonrasib and Beyond: Pan‐RAS Inhibition, Resistance, and Next‐Generation Strategies
Cancer Science, EarlyView.ABSTRACT RAS proteins have long been considered difficult therapeutic targets, but allele‐selective inhibitors established the clinical tractability of mutant RAS. Daraxonrasib (RMC‐6236), an oral pan‐RAS inhibitor, has now extended this concept by targeting multiple mutant and wild‐type RAS proteins.
Ryo Honda
wiley +1 more source
Cancer Science, EarlyView.Intravenous (IV) or intratumoral (IT) cetuximab distribution in A431 tumor (essence of Figure 2). ABSTRACT Near‐infrared photoimmunotherapy (NIR‐PIT) is a new type of cancer treatment that specifically kills target cells while sparing normal tissue. This treatment induces cancer cell death by activating a photoreactive dye with near‐infrared light in ...
Miyu Kano +9 more
wiley +1 more source
Advances in Spatial Heterogeneity and Cellular Localization Specificity of Intratumoral Bacteria
Cancer Science, EarlyView.Spatial localization of intratumoral bacteria governs their functional roles in tumor progression, metastasis, and treatment responses, with guiding significance for clinical management, as reviewed across three spatial paradigms. ABSTRACT Bacteria in tumors are increasingly recognized to be a part of the tumor microenvironment and their biological ...
Minlan Ren +11 more
wiley +1 more source
Cancer Science, EarlyView.INHBB secreted by colorectal cancer cells activates ACVR2B‐SMAD signaling to induce CD8+ T‐cell exhaustion and drive tumor progression. SB431542 blocks this oncogenic immune‐suppressive axis. ABSTRACT To investigate the expression pattern, biological functions and regulatory mechanisms of inhibin beta B (INHBB) in colorectal cancer (CRC), and to ...
Guanghui Liu +5 more
wiley +1 more source
Cell Proliferation, EarlyView.This study presents an NDs‐mediated localised combination strategy that integrates autophagy inhibition with low‐dose ATO sensitization, enabling effective tumour suppression while enhancing safety. NDs‐mediated autophagy blockade enhances ATO efficacy while minimising systemic toxicity, highlighting a promising approach for solid tumour treatment ...
Yiliu Wang +8 more
wiley +1 more source