Results 141 to 150 of about 131,504 (305)
, 2018 Granulomatous amoebic encephalitis caused by Acanthamoeba is a rare entity mainly affecting immunocompromised patients. We reported a case of Acanthamoeba encephalitis of a 1-year-old immunocompetent child and described the CT and MRI findings of the ...
Part Time Noor Husna binti Mohamad Zayadi
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Advanced Science, EarlyView.Repurposing the dense tumor stroma from a physical barrier into an anchoring scaffold, an engineered oncolytic adenovirus encoding IL15C‐CBD overcomes the immunosuppressive microenvironment in triple‐negative breast cancer. Intratumoral viral replication secretes this collagen‐anchored immunocytokine, forming a localized cytokine depot.
Yaqi Yang +14 more
wiley +1 more source
TP53 Loss Elevates NF‐κB‐IFN‐β‐MHC‐Ia Signaling to Promote NK Cell Resistance in Osteosarcoma
Advanced Science, EarlyView.TP53 loss in a transforming or osteosarcoma cell promotes cytosolic DNA accumulation, activating NF‐κB‐dependent IFN‐β production. Autocrine IFN‐β signaling increases cell‐surface HLA‐Ia expression, strengthens inhibitory KIR signaling in natural killer cells, and thereby enables the affected cell to evade NK cell‐mediated cytotoxicity.
Guihui Qin +9 more
wiley +1 more source
Advanced NanoBiomed Research, EarlyView.This study systematically compares small extracellular vesicles (sEVs) derived from four neural cell lines, revealing how cellular origin shapes vesicle biophysical properties and proteomic cargo. Distinct, lineage‐specific signatures linked to neuronal, astrocytic, and microglial functions are identified, highlighting the importance of cell source ...
Muhammad Waqas Salim +4 more
wiley +1 more source
Life-threatening periocular pseudomonal necrotizing fasciitis in an immunocompetent infant
Purpose: Necrotizing fasciitis, a severe soft tissue bacterial infection, is uncommon in the periocular region due to its rich blood supply. This report highlights a rare case in an immunocompetent infant.
Nathan Pirakitikulr +2 more
core +1 more source
Childhood herpes zoster: A clustering of ten cases
Indian Journal of Dermatology, 2009 Herpes zoster occurs due to reactivation of the latent varicella zoster virus and is usually a disease of the elderly. Childhood herpes zoster is believed to be rare, though recent studies suggest increasing incidence in children.
Prabhu Smitha +3 more
doaj
Pulmonary toxoplasmosis in the immunocompetent
Pan African Medical JournalA 29-year-old male milk vendor, a non-smoker with no comorbid conditions, presented with complaints of fever, cough, hemoptysis, and loss of weight for the past 3 weeks. The complete blood count was normal, and all viral markers were negative. The chest X-ray was unremarkable, and the computed tomography (CT) scan of the thorax showed ground glass ...
openaire +3 more sources
Animal Research and One Health, EarlyView.Intensive or organic farming systems may expose pigs to management or environmental challenges. Our preliminary results concluded that organic farming might enhance adaptive immune function, showing that improvements in welfare can translate into measurable immunological benefits, based on the correlation between welfare assessment and physiological ...
Dorotea Ippolito +15 more
wiley +1 more source
Animal Research and One Health, EarlyView.Our paper systematically reviews the intestinal structure, function, and microbiota of ostriches, along with strategies for improving their gut health. We analyze how these factors collectively influence intestinal homeostasis and ostrich welfare, emphasizing probiotics as a promising intervention to enhance gut health, boost population well‐being, and
Zi‐Qun Zhang +6 more
wiley +1 more source
Roseomonas Mucosa Bacteremia in an Immunocompetent Child
We report a case of bacteremia associated with Roseomonas mucosa isolated from an immunocompetent pediatric patient with no prior history of infection and ...
Shalini Goldar +3 more
core +1 more source