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Impact of COVID-19 on immunocompromised populations during the Omicron era: insights from the observational population-based INFORM study

Lancet Regional Health - Europe, The, 2023
Summary Background Immunocompromised individuals are not optimally protected by COVID-19 vaccines and potentially require additional preventive interventions to mitigate the risk of severe COVID-19.
Nahila Justo, Samira Bell, Sudhir Venkatesan   +2 more
exaly   +2 more sources

SARS-CoV-2 in immunocompromised individuals

Immunity, 2022
Immunocompromised individuals and particularly those with hematologic malignancies are at increased risk for SARS-CoV-2-associated morbidity and mortality due to immunologic deficits that limit prevention, treatment, and clearance of the virus ...
Susan Dewolf, Santosha Vardhana, Mini Kamboj   +2 more
exaly   +2 more sources

Multidrug-Resistant Bacteria in Immunocompromised Patients

Pharmaceuticals
The increasing incidence of antibiotic resistance in bacteria is a major problem in terms of therapeutic options, especially in immunocompromised patients, such as patients from intensive care units (ICUs), HIV-positive patients, patients with ...
Olivia Dorneanu, Luminita Smaranda Iancu, Felicia Trofin   +2 more
exaly   +2 more sources

Vaccination of Immunocompromised Cats [PDF]

Viruses, 2022
Immunocompromise is a common condition in cats, especially due to widespread infections with immunosuppressive viruses, such as feline immunodeficiency virus (FIV) and feline leukaemia virus (FeLV), but also due to chronic non-infectious diseases, such as tumours, diabetes mellitus, and chronic kidney disease, as well as treatment with ...
Hartmann, Katrin, Möstl, Karin, Lloret, Albert, Thiry, Etienne, Addie, Diane D, Belák, Sándor, Boucraut-Baralon, Corine, Egberink, Herman, Frymus, Tadeusz, Hofmann-Lehmann, Regina, Lutz, Hans, Marsilio, Fulvio, Pennisi, Maria Grazia, Tasker, Séverine, Truyen, Uwe, Hosie, Margaret J   +15 more
openaire   +8 more sources

Efficacy of covid-19 vaccines in immunocompromised patients: systematic review and meta-analysis

British medical journal, 2022
Objective To compare the efficacy of covid-19 vaccines between immunocompromised and immunocompetent people. Design Systematic review and meta-analysis.
YB Li, S. Wong, L. Chai, S. Lee, M. Lee, M. D. Muthiah, S. Tay, C. B. Teo, B. Tan, Y. Chan, R. Sundar, Y. Soon   +11 more
semanticscholar   +1 more source

HIV-2 Vpx neutralizes host restriction factor SAMHD1 to promote viral pathogenesis

Scientific Reports, 2021
SAMHD1, a human host factor found in myeloid cells which restricts HIV-1 replication. It depletes the dNTPs pool for viral cDNA syntheses, thus preventing the viral replication in the cells.
Ahlam Mohamed, Talal Bakir, Huda Al-Hawel, Ibtihaj Al-Sharif, Razan Bakheet, Lubna Kouser, Valarmathy Murugaiah, Maha Al-Mozaini   +7 more
doaj   +1 more source

Human immunodeficiency virus in Saudi Arabia: Current and future challenges

Journal of Infection and Public Health, 2023
Introduction: Understanding the pathophysiology of HIV infection has been crucial to the design of effective anti-viral strategies. HIV infection is declining worldwide due to early diagnosis and the effective long-term use of anti-retroviral therapy ...
Maha Al-Mozaini, Tahani Al-Rahabani, Qais Dirar, Tala Alashgar, Ali A. Rabaan, Waleed Murad, Jawaher Alotaibi, Abdulrahman Alrajhi   +7 more
doaj   +1 more source

Pathogenesis of human cytomegalovirus in the immunocompromised host

Nature Reviews Microbiology, 2021
Human cytomegalovirus (HCMV) is a herpesvirus that infects ~60% of adults in developed countries and more than 90% in developing countries. Usually, it is controlled by a vigorous immune response so that infections are asymptomatic or symptoms are mild ...
P. Griffiths, M. Reeves
semanticscholar   +1 more source

Evaluation of two molecular detection platforms for gastroenteritis pathogens in treated sewage water in the Eastern province of Saudi Arabia

Scientific Reports, 2022
The ability to screen environmental water samples for gastroenteritis pathogens, particularly viruses remains challenging. Here, we investigated the presence of enteric viruses in treated sewage effluent water samples collected from a cooling tower in ...
Fawaz A. Al-Wohaib, Ibtihaj Al-Sharif, Hassan Al-Zain, Donna Murad, Layla Al-Harbi, Maha Al-Mozaini   +5 more
doaj   +1 more source

Implementation of a Routine Screening Program for Latent Tuberculosis Infection among Patients with Acute Leukemia at a Canadian Cancer Center

Current Oncology, 2022
Background: Screening for latent tuberculosis infection (LTBI) in patients with hematological malignancy is recommended because of their increased risk of tuberculosis (TB). We assessed the utility of tuberculin skin test (TST) screening in patients with
Rbab Taha, Sagar Kothari, Farid Foroutan, Melissa Gitman, Vikas Gupta, Tram Nguyen, Coleman Rotstein   +6 more
doaj   +1 more source