Results 41 to 50 of about 284,282 (314)

Epidemiological and Clinical Characteristics of Non-Typhoidal Salmonella Bloodstream Infections in Central Israel: A Case-Control Study

Microorganisms, 2022
Non-typhoidal Salmonella (NTS) infection continues to be a significant cause of morbidity. In addition to gastroenteritis (GE), NTS may cause bloodstream infections (BSI).
Yael Israel, Khitam Muhsen, Assaf Rokney, Amos Adler   +3 more
doaj   +1 more source

Outcome of COVID-19 in hospitalised immunocompromised patients: An analysis of the WHO ISARIC CCP-UK prospective cohort study

medRxiv, 2022
Background Immunocompromised patients may be at higher risk of mortality if hospitalised with COVID-19 compared with immunocompetent patients. However, previous studies have been contradictory.
L. Turtle, M. Thorpe, T. Drake, M. Swets, C. Palmieri, C. Russell, A. Ho, S. Aston, D. Wootton, A. Richter, T. D. de Silva, H. Hardwick, G. Leeming, Andrew Law, P. Openshaw, E. Harrison, J. Baillie, M. Semple, A. Docherty   +18 more
semanticscholar   +1 more source

Development of transplantable B-cell lymphomas in the MHC-defined miniature swine model

Cancer Cell International, 2019
Background Establishment of transplantable tumors in clinically relevant large animals allows translational studies of novel cancer therapeutics. Methods Here we describe the establishment, characterization, and serial transplantation of a naturally ...
Alec R. Andrews, Zhaohui Wang, Robert A. Wilkinson, Jay A. Fishman, David H. Sachs, Nalu Navarro-Alvarez, Christene A. Huang   +6 more
doaj   +1 more source

Factors Associated with Severe Outcomes Among Immunocompromised Adults Hospitalized for COVID-19 — COVID-NET, 10 States, March 2020–February 2022

MMWR. Morbidity and mortality weekly report, 2022
Immunocompromised persons are at increased risk for severe COVID-19-related outcomes, including intensive care unit (ICU) admission and death (1). Data on adults aged ≥18 years hospitalized with laboratory-confirmed COVID-19 from 10 U.S.
Jason Robert C Singson, P. D. Kirley, H. Pham, G. Rothrock, I. Armistead, J. Meek, E. Anderson, L. Reeg, R. Lynfield, S. Ropp, A. Muse, C. Felsen, M. Sutton, H. Talbot, F. Havers, C. Taylor, A. Reingold, S. Chai, N. Alden, Kimberley Yousey-Hindes, K. Openo, Erica Bye, Mark Montoya, G. Barney, Kevin Popham, N. Abdullah, W. Schaffner   +26 more
semanticscholar   +1 more source

Clinical Characteristics and Outcomes of Immunocompromised Patients With Coronavirus Disease 2019 Caused by the Omicron Variant: A Prospective, Observational Study

medRxiv, 2022
Summary Background In the general population, illness after infection with the SARS-CoV-2 Omicron variant is less severe compared with previous variants. Data on the disease burden of Omicron in immunocompromised patients are lacking. We investigated the
S. R. K. Malahe, R. Hoek, Virgil A. S. H. Dalm, A. Broers, C. D. den Hoed, O. Manintveld, C. Baan, Charlotte M. van Deuzen, G. Papageorgiou, H. Bax, J. V. van Kampen, M. Hellemons, M. Kho, R. D. de Vries, R. Molenkamp, M. Reinders, B. Rijnders   +16 more
semanticscholar   +1 more source

Diagnosis of severe respiratory infections in immunocompromised patients

Intensive Care Medicine, 2020
An increasing number of critically ill patients are immunocompromised. Acute hypoxemic respiratory failure (ARF), chiefly due to pulmonary infection, is the leading reason for ICU admission. Identifying the cause of ARF increases the chances of survival,
É. Azoulay, L. Russell, A. Van de Louw, V. Metaxa, P. Bauer, P. Póvoa, J. G. Montero, I. Loeches, S. Mehta, K. Puxty, P. Schellongowski, J. Rello, D. Mokart, V. Lemiale, Adrien Mirouse   +14 more
semanticscholar   +1 more source

Effectiveness of a Third Dose of Pfizer-BioNTech and Moderna Vaccines in Preventing COVID-19 Hospitalization Among Immunocompetent and Immunocompromised Adults — United States, August–December 2021

MMWR. Morbidity and mortality weekly report, 2022
COVID-19 mRNA vaccines (BNT162b2 [Pfizer-BioNTech] and mRNA-1273 [Moderna]) provide protection against infection with SARS-CoV-2, the virus that causes COVID-19, and are highly effective against COVID-19-associated hospitalization among eligible persons ...
M. Tenforde, Manish M Patel, M. Gaglani, A. Ginde, D. Douin, H. Talbot, J. Casey, N. Mohr, A. Zepeski, T. McNeal, S. Ghamande, K. Gibbs, D. Files, D. Hager, A. Shehu, M. Prekker, H. Erickson, M. Gong, A. Mohamed, N. Johnson, Vasisht Srinivasan, J. Steingrub, I. Peltan, Samuel M. Brown, E. Martin, A. Monto, Akram Khan, C. Hough, L. Busse, A. Duggal, Jennifer G. Wilson, N. Qadir, Steven Y. Chang, C. Mallow, C. Rivas, H. Babcock, Jennie H. Kwon, M. Exline, M. Botros, A. Lauring, N. Shapiro, N. Halasa, J. Chappell, Carlos G. Grijalva, T. Rice, I. D. Jones, William B. Stubblefield, A. Baughman, K. Womack, J. Rhoads, C. Lindsell, K. Hart, Yuwei Zhu, Eric A. Naioti, K. Adams, N. Lewis, D. Surie, M. McMorrow, W. Self   +58 more
semanticscholar   +1 more source

COVID-19 in immunocompromised populations: implications for prognosis and repurposing of immunotherapies

Journal for ImmunoTherapy of Cancer, 2021
SARS-CoV-2 is the virus responsible for the COVID-19 pandemic. COVID-19 has highly variable disease severity and a bimodal course characterized by acute respiratory viral infection followed by hyperinflammation in a subset of patients with severe disease.
J. Goldman, P. Robinson, T. Uldrick, P. Ljungman   +3 more
semanticscholar   +1 more source

Significant Mortality Reduction from Severe Pneumocystis jirovecii Pneumonia in People Living with HIV and Treated in the Intensive Care Unit, Croatia, 2002–2023

Pathogens
Pneumocystis jirovecii pneumonia (PCP) remains a frequent cause of intensive care unit (ICU) admission among people living with HIV (PLWH), despite widespread antiretroviral therapy (ART) use. We conducted a retrospective cohort study of 39 PLWH with PCP
Filip Glavač, Lucija Dragošević, Josip Begovac, Marko Kutleša, Anita Atelj, Martina Vargović, Šime Zekan, Đivo Ljubičić, Ana Čičmak, Marija Santini   +9 more
doaj   +1 more source

Rhino-oculo-cerebral aspergillus and mucor co-infections in an immunocompromised patient with type 2 diabetes mellitus

Medical Journal of Dr. D.Y. Patil University, 2014
Mucormycosis are pathogenic moulds of the mucorales species usually occurring in immunocompromised patients or in patients with uncontrolled diabetes mellitus.
Kalidas Rit, Rajdeep Saha, Rupali Dey, Gautam Barik   +3 more
doaj   +1 more source