Results 101 to 110 of about 1,620,419 (294)

Case Report and Literature Review: HHV-6-Associated Meningoencephalitis in an Immunocompetent Adult

, 2008
Human herpesvirus type 6 (HHV-6) has been well described as an agent of meningoencephalitis in post-haematopoietic stem cell transplantation patients, but is a rare cause of meningoencephalitis in immunocompetent adults.
Myers, James W., Moorman, Jonathan P., Trabue, Christopher, Bloch, Karen C.   +3 more
core   +1 more source

Legionella lymphadenitis in immunocompetent adult: Case report

IDCases
Introduction: Extrapulmonary legionella disease is rare and occasionally reported in immunocompromised patients; it includes lymphadenitis, panniculitis, hepatitis, atrio-ventricular block, arthritis, prosthetic valve endocarditis and myocarditis.
Johny Salem, Fadi Fares, Rana El-Haddad, Mirna Fares, Gilbert El-Helou   +4 more
doaj   +1 more source

Plasmablastic Lymphoma of Maxilla in an Immunocompetent Adult

Journal of Maxillofacial and Oral Surgery
Plasmablastic lymphoma (PBL) is an aggressive non-Hodgkin's lymphoma often found in immunocompromised individuals, especially those with HIV. It features large neoplastic cells resembling plasmablasts and plasma cells, making it challenging to distinguish from plasma cell myeloma.
Mohammad Slahuddin Ahmed, Raja Chhabra, Sajjan Rajpurohit, Nivedita Patnaik, Md. Ali Osama   +4 more
openaire   +3 more sources

PTBP1‐Mediated Alternative Splicing of DNAJB6 Promotes Everolimus Resistance in Clear Cell Renal Cell Carcinoma via EIF4B/PKIB/AKT/mTOR Positive Feedback Loop

Advanced Science, EarlyView.
PTBP1‐mediated alternative splicing drives a pathogenic switch to the DNAJB6b isoform in everolimus‐resistant clear cell renal cell carcinoma. This splicing event programs a positive feedback loop including EIF4B/PKIB/AKT/mTOR, promoting aggressive therapy resistance.
Xiu‐wu Pan, Hong‐feng Zheng, Mu‐chen Li, Jia‐lin Zhou, Hang‐biao Zhang, Dong‐hao Lyu, Yi‐fan Tang, Tian‐yue Yang, Yi‐fan Liu, Zi‐chang Liu, Wen‐jie Ma, Yuan‐bo Zong, Jian‐gui Liu, Zi‐xuan Gong, Hao Zhang, Ke‐qin Dong, Wang Zhou, Jian‐qin Ye, Xin‐gang Cui   +18 more
wiley   +1 more source

First reported case of vertebral osteomyelitis due to Erysipelothrix rhusiopathiae

IDCases, 2018
We describe a case of acute vertebral osteomyelitis with associated prevertebral abscess due to Erysipelothrix rhusiopathiae in an immunocompetent adult with recent known traumatic inoculation from the barb of a fish.
Matthew L. Lorenz, Tara C. Bouton, Angela M. Caliendo   +2 more
doaj   +1 more source

Asymmetric Structure‐Driven Functional Synergy: A Multistimuli‐Activated Janus Nanomotor for Self‐Amplifying NO Cascade Therapy

Advanced Science, EarlyView.
The Janus nanomotors leverage an “asymmetric structure‐driven functional synergy” strategy to orchestrate spatiotemporally coordinated catalytic functions, in situ self‐amplifying NO generation, and deep tumor penetration, thereby enabling controllable, sustained, and uniform NO generation within the tumor microenvironment.
Chengcheng Li, Yu Zhang, Yu Chen, Lingyun He, Xian Shen, Weijian Sun, Hongbo Zhang   +6 more
wiley   +1 more source

Human Herpesvirus‐6 Infectious Meningitis With Lymphadenitis in an Immunocompetent Adult

Brain and Behavior
Purpose Human Herpesvirus 6 (HHV‐6) infections are primarily observed in immunocompromised individuals, such as those with acquired immunodeficiency syndrome or organ transplant recipients.
Yu Xie, Chenrui Zhang, Mingchi Ma, Ziqian Yin, Liqian Chen, Yimiao Yang, Shuang Wu, Yuanteng Fan, Yan Xu, Dan He   +9 more
doaj   +1 more source

Parvovirus B19 in an Immunocompetent Adult Patient with Acute Liver Failure: An Underdiagnosed Cause of Acute Non-A-E Viral Hepatitis [PDF]

, 2005
There are occasional pediatric reports of parvovirus B19-associated transient acute hepatitis and hepatic failure. A case of a 34-year-old immunocompetent woman who developed severe and prolonged but self-limited acute hepatitis and myelosuppression ...
William R Bowie, Robert Coupland, J Kee Ho, Gayatri M Sreenivasan, Bakul I Dalal, Mel Krajden, Susan PL Tha, Eric M Yoshida   +7 more
core   +1 more source

Platycodon grandiflorus–Derived Nanovesicles Sensitize Gastric Cancer to T Cell Killing via Ferroptosis‐Driven Membrane Mechanical Remodeling

Advanced Science, EarlyView.
Plant‐derived nanovesicles from Platycodon grandiflorus act as bioactive lipid delivery platforms that transport γ‐linolenic acid into gastric cancer cells. This lipid cargo promotes ferroptotic lipid peroxidation, remodels membrane mechanics, and increases tumor‐cell susceptibility to cytotoxic T‐cell attack.
Jian Wu, Ruijuan Zhang, Yixin Duan, Shuqi Huo, Xiang Zhang, Yibin Xing, Lingjing Ma, Tiran Jiang, Xingyu Chen, Qingmin Sun   +9 more
wiley   +1 more source

Optic Neuritis in an Adult Patient with Chickenpox

Case Reports in Ophthalmological Medicine, 2012
Central nervous system involvement in a patient with primary infection with Varicella zoster virus is rare, especially in the immunocompetent adult. In particular, isolated optic neuritis has been described in a small number of cases. The authors present
Ana Rita Azevedo, Rita Simões, Filipe Silva, Susana Pina, Cristina Santos, Peter Pêgo, Filomena Silva, Susana Teixeira   +7 more
doaj   +1 more source