Results 71 to 80 of about 1,620,419 (294)
Adeno‐associated virus serotype 2 capsid variants for improved liver‐directed gene therapy
Hepatology, EarlyView., 2022 Abstract Background and Aims Current liver‐directed gene therapies look for adeno‐associated virus (AAV) vectors with improved efficacy. With this background, capsid engineering is explored. Whereas shuffled capsid library screenings have resulted in potent liver targeting variants with one first vector in human clinical trials, modifying natural ...
Nadja Meumann +25 more
wiley +1 more source
Mediterranean Journal of Hematology and Infectious Diseases, 2014 : Though CMV infections are not very rare in immuno-competent individuals, CMV leading to hemolytic anemia is a rare phenomenon. We report a case of cold agglutinin mediated hemolytic anemia in one such patient due to CMV infection.
Dr. Ajay Asranna +3 more
doaj
Brain abscess in immunocompetent adult patients
Revue Neurologique, 2019 Brain abscess is a focal infection of the brain due to contiguous spread of pathogens following otitis, sinusitis, neurosurgery or traumatic brain injury or through hematogenous dissemination. Classical symptoms consisting of headache, fever, and focal signs may be absent on admission and brain MRI with contrast plays a major role in diagnosis. Initial
Cantiera, M. +2 more
openaire +5 more sources
Advanced Science, EarlyView.Proposed model of CHST1‐associated immune remodeling in triple‐negative breast cancer. In CHST1‐low tumors, greater nuclear accumulation of NKRF is associated with repression of an NF‐κB‐related CCL20 transcriptional program and an immune‐inflamed microenvironment.
Shu‐Hao Jiang +6 more
wiley +1 more source
Advanced Science, EarlyView.Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang +10 more
wiley +1 more source
, 2018 Overt aseptic meningitis rarely complicates varicella-zoster virus (VZV) reactivation in young and immunocompetent adults. Many of the cases of VZV meningitis are associated with an exanthem.
Ioannis Gialamas +4 more
core +1 more source
Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma
Advanced Science, EarlyView.This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert +8 more
wiley +1 more source
Successful Treatment of Human Herpesvirus 6 Encephalomyelitis in Immunocompetent Patient
Emerging Infectious Diseases, 2004 We report the case of human herpesvirus 6 (HHV-6) encephalomyelitis in an immunocompetent patient, which was confirmed by viral amplification from cerebrospinal fluid. Cidofovir was used followed by ganciclovir because of an adverse effect to probenecid.
Eric Denes +5 more
doaj +1 more source
A Case of Cytomegalovirus Gastroduodenitis in an Immunocompetent Adult
Kansenshogaku Zasshi, 2013 A 58-year-old male developed epigastric discomfort and high fever in 2010. Complete blood count showed leukocytosis and a small number of atypical lymphocytes. Gastric endoscopy revealed multiple gastroduodenal erosions and ulcers. Biopsy specimens were obtained and pathological examination demonstrated cytomegalic inclusion bodies.
ONAKA, Takashi +2 more
openaire +3 more sources
Acquired multifocal tufted angiomas in an immunocompetent young adult
, 2011 Tufted angioma (TA) is a rare benign vascular neoplasm, localized to the skin and subcutaneous tissues, occurring primarily on the trunk and extremities of children.
SudipKumar Ghosh +7 more
core +1 more source