Results 101 to 110 of about 249,445 (302)

Cutaneous mucormycosis arising in the skin folds of immunocompromised patients: A case series

JAAD Case Reports, 2021
Renajd Rrapi, BA, Sidharth Chand, BA, Rebecca Gaffney, MD, Jennifer A. Lo, MD, PhD, Jeffrey S. Smith, MD, PhD, Fan Di Xia, MD, Steven T. Chen, MD, MPH, MS-HPEd, Lyn M. Duncan, MD, Ruth K. Foreman, MD, PhD, Rebecca I. Hartman, MD, MPH, Mai P. Hoang, MD, Adriano Piris, MD, Andrew C. Walls, MD, Daniela Kroshinsky, MD, MPH   +13 more
doaj   +1 more source

Gyriform Susceptibility Rim in Early Progressive Multifocal Leukoencephalopathy

Annals of Neurology, EarlyView.
Thor Linnet, Karan Dixit, Shailee Shah
wiley   +1 more source

Viral Dynamic Model‐Informed Dose Selection of Mosnodenvir Prophylaxis against DENV‐3 in a Controlled Human Infection Model

Clinical Pharmacology &Therapeutics, EarlyView.
Dengue virus (DENV) infection is a significant global health threat. Mosnodenvir (JNJ‐64281802) is a pan‐serotype small molecule antiviral blocking DENV replication. A Phase IIa study (NCT05048875) evaluated the antiviral activity, safety, and pharmacokinetics of mosnodenvir as prophylaxis against DENV‐3 in a controlled human infection model (CHIM).
Nele Goeyvaerts, Xavier Woot de Trixhe, Martine Neyens, Thomas N. Kakuda, Liesbeth Van Wesenbeeck, Annemie Buelens, Freya Rasschaert, Anna Durbin, Oliver Ackaert   +8 more
wiley   +1 more source

CAQ Corner: Immune‐mediated complications

, 2022
Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley   +1 more source

Fungal Infections in Immunocompromised Hosts [PDF]

, 2019
This book is a printed edition of the Special Issue Fungal Infections in Immunocompromised Hosts that was published in ...
Kontoyiannis, Dimitrios P., Slavin, Monica   +1 more
core   +1 more source

Phase I Evaluation of Siltartoxatug, a First‐in‐Class Anti‐Tetanus Monoclonal Antibody: Safety, Pharmacokinetics and Pharmacodynamics in Healthy Australian and Chinese Populations

Clinical Pharmacology &Therapeutics, EarlyView.
Siltartoxatug, a first‐in‐class monoclonal antibody targeting tetanus toxin for post‐exposure prophylaxis, was evaluated in two phase I trials in Australian and Chinese healthy adults. In these randomized, double‐blind, placebo‐controlled, dose‐escalation studies, participants received a single intramuscular injection of siltartoxatug (10–250 μg/kg) or
Xinyu Liu, Zhigang Liu, Xiaohu Kuang, Yueming Wang, Xiaoyi Liu, Jiyuan Ding, Xia Zhou, Xin Zhou, Qianyu Liang, Meizhuo Zhang, Hao Zhao, Qingqing Tan, Weihong Zheng, Huaxin Liao, Charlotte Lemech, Wanmei Wang   +15 more
wiley   +1 more source

Endogenous Trigeminal Neurons Induce Schwann Differentiation of Donor Stem Cells in Dental Pulp Regeneration via Reciprocal Extracellular Vesicles Interplay

Exploration, EarlyView.
Our study demonstrates that the host TG coordinates with heterologously implanted SHED to regenerate functional dental pulp through reciprocal EVs’ interplay. EVs derived from implanted stem cells migrate to the host TG to activate axonal regeneration.
Wanmin Zhao, Wenzhe Wang, Jia Guo, Jiani Liu, Wei Wang, Dihao Tao, Jiayi Dong, Zhonghan Li, Shiyu Liu, Songtao Shi, Tao Chen, Yan Jin, Bei Li   +12 more
wiley   +1 more source

Clinical Outcomes of Hospitalized Immunocompromised Patients With COVID-19 and the Impact of Hyperinflammation: A Retrospective Cohort Study [PDF]

Xinxin Zhang,1,* Xiaobo Han,1,2,* Chenglong Li,3,4,* Junchang Cui,1,2 Xin Yuan,5 Jiguang Meng,6,7 Zhihai Han,8 Xinjie Han,1 Wei Chen,8 Junchen Xiong,6,7 Wuxiang Xie,9,10 Lixin Xie1,2 1College of Pulmonary and Critical Care Medicine, The ...
Xiong J, Xie W, Li C, Zhang X, Cui J, Chen W, Han X, Xie L, Han Z, Yuan X, Meng J   +10 more
core  

Sporotrichosis In Immunocompromised Hosts

, 2019
Sporotrichosis is a global implantation or subcutaneous mycosis caused by several members of the genus Sporothrix, a thermo-dimorphic fungus. This disease may also depict an endemic profile, especially in tropical to subtropical zones around the world ...
Flavio Queiroz-Telles, Renata Buccheri, Gil Benard   +2 more
core   +1 more source

Potential for conflict between urban coyotes and people experiencing unsheltered homelessness

Frontiers in Ecology and the Environment, EarlyView.
Across North America, both unsheltered homelessness and human–coyote (Canis latrans) conflict are increasing, but the relationship between these phenomena has not been thoroughly explored. We synthesize literature‐based evidence with anecdotal observations that occurred during a 15‐year study of coyotes in Edmonton, Canada, to describe three likely ...
Sage Raymond, Jeff Rose, Colleen Cassady St Clair   +2 more
wiley   +1 more source