Results 181 to 190 of about 1,309 (221)
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Immunoinfertility: A Case Study with Implications for Immunocontraception
Archives of Andrology, 1995A detailed case history was compiled on a couple who have had primary infertility for more than 20 years. The history and further laboratory investigations indicated that the infertility was caused by high-titre sperm antibodies in the female. The antibodies blocked sperm-zona binding and reacted with a prominent band at 65 kD in Western blots ...
G N, Clarke, D Y, Liu, H W, Baker
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Modelling immunocontraception in disseminating systems
Reproduction, Fertility and Development, 1997Vectored immunocontraception is a novel technology and simple models are described to help predict whether, and how, it might work. That is, given that an effective immunocontraceptive agent can be produced, and given that it can be inserted into a microparasitic or macroparasitic infective vector, would the vector persist and reach a high prevalence ...
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Use of cauda epididymis extract as immunocontraceptive
Contraception, 2002The objective of this study was to evaluate use of a cauda epididymis extract (CEE) as an immunocontraceptive in rats. Twenty-two rats in puberty or 19 rats that gave birth once (primipara) were immunized with intraperitoneal (IP) injection of CEE. Rats in puberty received one or two injections of CEE containing 1.5 x 10(9) sperm/mL, while primipara ...
Ali, Risvanli +5 more
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Study for the male immunocontraception of wild animals using sperm antigens.
Journal of Reproductive Immunology, 2022J. Noguchi
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Development of New Immunocontraceptives‐Industrial Perspective
American Journal of Reproductive Immunology, 1996Contraception has been practiced for thousands of years. Nevertheless, it took until the late 1950s and early 1960s before a major breakthrough in contraceptive technology was achieved by the introduction of oral hormonal contraceptives. However, we have not succeeded in the development of a non‐hormonal contraceptive that is comparable to the pill ...
U F, Habenicht, G, Stock
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Development of combined vaccines for rabies and immunocontraception
Vaccine, 2009Rabies prevention and appropriate population management of free-ranging animals have an important role to play in the eventual elimination of rabies in dogs. An effective sterilant based on rabies vaccines has the potential to create a supportive measure of public acceptability and to reduce associated clinic visit costs.
Xianfu, Wu +4 more
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Comparative efficacy of two immunocontraceptive vaccines
Vaccine, 1997As part of our research program to develop immunocontraception as a wildlife management tool, we compared the physiological responses of wild Norway rats (Rattus norvegicus) to two immunocontraceptive vaccines; one involved mouse zona pellucida peptide (MZPP); the other involved gonadotropin releasing hormone (GnRH).
L A, Miller +3 more
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The Potential of the Zona Pellucida as a Target for Immunocontraception
American Journal of Reproductive Immunology, 1996PROBLEM: To investigate the contraceptive potential of the zona pellucida. METHOD: Generation of antibodies against native and recombinant zona glycoproteins which have then been assessed for their capacity to disrupt sperm‐zona interaction in vivo and in vitro.
R J, Aitken, M, Paterson, M, van Duin
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Virus-vectored immunocontraception of feral mammals
Reproduction, Fertility and Development, 1994The potential value of immunosterilization as a means to control species of wildlife that are widespread, numerous and undesirable is assessed. Key questions about the efficacy of fertility control and the means for delivering antigens expressed in recombinant viral vectors are discussed and the legal and social concerns that relate to its possible ...
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