Results 11 to 20 of about 174,366 (328)

Breast Carcinoma Metastasis to Thyroid Gland Masquerading as Nodular Goitre: A Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2023
Thyroid gland, despite being a highly vascular organ, is an extremely unusual site for metastasis from primary carcinoma like breast. We, hereby, report a case of metastatic lesion in the thyroid with breast carcinoma as a primary, in a 55-year-old ...
Anita Nangia, Shruti Chauhan
doaj   +1 more source

Automated immunostaining platform in cytology

Journal of Cytology, 2021
Background: In the modern era, immunocytochemistry (ICC) is an essential part of investigations. There is now an increasing workload of ICC in laboratories.
Shelly Sharma, Pranab Dey
doaj   +1 more source

Transgenic Overexpression of LARGE Induces alpha-Dystroglycan Hyperglycosylation in Skeletal and Cardiac Muscle [PDF]

, 2010
Background: LARGE is one of seven putative or demonstrated glycosyltransferase enzymes defective in a common group of muscular dystrophies with reduced glycosylation of alpha-dystroglycan.
Brockington, M, Brown, SC, Cirak, S, Liu, K, Muntoni, F, Sharp, PS, Torelli, S, Wells, DJ   +7 more
core   +14 more sources

Muscle calcium stress cleaves junctophilin1, unleashing a gene regulatory program predicted to correct glucose dysregulation

eLife, 2023
Calcium ion movements between cellular stores and the cytosol govern muscle contraction, the most energy-consuming function in mammals, which confers skeletal myofibers a pivotal role in glycemia regulation. Chronic myoplasmic calcium elevation (“calcium
Eshwar R Tammineni, Lourdes Figueroa, Carlo Manno, Disha Varma, Natalia Kraeva, Carlos A Ibarra, Amira Klip, Sheila Riazi, Eduardo Rios   +8 more
doaj   +1 more source

Modulation of endothelial factors activity in human endothelial cells in influenza A(H1N1)pdm09 virus infection

Вопросы вирусологии, 2021
Introduction. Influenza A virus infection can lead to endothelial dysfunction (ED), including apoptosis of endothelial cells and modulation of endothelial factor activities.
V. A. Marchenko, S. V. Barashkova, I. A. Zelinskaya, Ya. G. Toropova, E. S. Ramsay, I. N. Zhilinskaya   +5 more
doaj   +1 more source

Shear Stress and RBC-NOS Serine1177 Phosphorylation in Humans: A Dose Response

Life, 2021
Red blood cells (RBC) express a nitric oxide synthase isoform (RBC-NOS) that appears dependent on shear stress for Serine1177 phosphorylation. Whether this protein is equally activated by varied shears in the physiological range is less described.
Jarod T. Horobin, Surendran Sabapathy, Lennart Kuck, Michael J. Simmonds   +3 more
doaj   +1 more source

Immunocytochemical Study of Rabbit-Polyclonal to Mycobacterium Tuberculosis, AB905: Improving Diagnostic of Tuberculous Lymphadenitis

Mutiara Medika, 2021
Tuberculous lymphadenitis (TBLN) is the most common form of extrapulmonary tuberculosis. However, the optimal diagnosis using Fine-Needle Aspiration Cytology (FNAC) or excisional biopsy is uncertain.
Humairah Medina Liza Lubis, Emni Purwoningsih, Ance Roslina, Muhammad Al Anas   +3 more
doaj   +1 more source

External quality assessment demonstrates that PD‐L1 22C3 and SP263 assays are systematically different

The Journal of Pathology: Clinical Research, 2020
PD‐L1 inhibitors are part of first line treatment options for patients with advanced non‐small cell lung cancer. PD‐L1 immunohistochemistry (IHC) assays act as either a companion or a complementary diagnostic. The purpose of this study is to describe the
Andrew Dodson, Suzanne Parry, Birgit Lissenberg‐Witte, Alex Haragan, David Allen, Anthony O'Grady, Emma McClean, Jamie Hughes, Keith Miller, Erik Thunnissen   +9 more
doaj   +1 more source

The Role of Chromatin Modifications in the Evolution of Giant Plant Genomes

Plants, 2023
Angiosperm genome sizes (GS) range ~2400-fold and comprise genes and their regulatory regions, repeats, semi-degraded repeats, and ‘dark matter’. The latter represents repeats so degraded that they can no longer be recognised as repetitive.
Andrew R. Leitch, Lu Ma, Steven Dodsworth, Jörg Fuchs, Andreas Houben, Ilia J. Leitch   +5 more
doaj   +1 more source

The Role of Immunocytochemical Markers to Differentiate Primary from Secondary Neoplastic Hepatic Masses: A Diagnostic Challenge on Cytology

Türk Patoloji Dergisi, 2021
Objective: It is challenging and difficult to differentiate primary from metastatic hepatic masses solely on cytology. The present study aimed to correlate cytomorphological spectrum of hepatic masses with immunocytochemical markers to differentiate ...
Jenna B BHATTACHARYA, Shyam Lata JAIN, Subbarayan DEVI   +2 more
doaj   +1 more source