Transgenic Overexpression of LARGE Induces alpha-Dystroglycan Hyperglycosylation in Skeletal and Cardiac Muscle [PDF]
, 2010 Background: LARGE is one of seven putative or demonstrated glycosyltransferase enzymes defective in a common group of muscular dystrophies with reduced glycosylation of alpha-dystroglycan.
Brockington, M +7 more
core +12 more sources
Calretinin Immunoreactivity in the VIIIth Nerve and Inner Ear Endorgans of Ranid Frogs
Frontiers in Neuroscience, 2021 Calcium-binding proteins are essential for buffering intracellular calcium concentrations, which are critical for regulating cellular processes involved in neuronal computations. One such calcium-binding protein, calretinin, is present in many neurons of
Ingrid Reichenberger +2 more
doaj +1 more source
Characterization and expression analysis of chymotrypsin after bacterial challenge in the mud crab, Scylla paramamosain [PDF]
Genetics and Molecular Biology, 2014 Chymotrypsin is one of the serine proteases families that have various biological functions. A chymotrypsin gene was isolated from hepatopancreas of the mud crab, Scylla paramamosain (designated SpCHY) in this study.
Jie Gong +5 more
doaj +1 more source
Expression of p63 and Bcl-2 in Malignant Thyroid Tumors and their Correlation with other Diagnostic Immunocytochemical Markers [PDF]
Journal of Clinical and Diagnostic Research, 2016 Introduction: Bcl-2 is a marker recently studied in thyroid tumours and proposed to have prognostic significance. p63 is expressed in a proportion of papillary thyroid carcinoma cases and may have a role in tumour progression.
Ashumi Gupta +3 more
doaj +1 more source
Quantification of neurodegeneration by measurement of brain-specific proteins [PDF]
, 2003 Quantification of neurodegeneration in animal models is typically assessed by time-consuming and observer-dependent immunocytochemistry. This study aimed to investigate if newly developed ELISA techniques could provide an observer-independent, cost ...
Baker, D. +5 more
core +1 more source
Chromogranin A in the olfactory system of the rat [PDF]
, 1990 The olfactory bulb of the rat contains chromogranin A at a similar level as the adrenal gland or the hypophysis as revealed by immunoblots. Olfactory chromogranin A also displays the same size as chromogranin A of endocrine cells.
Baker +32 more
core +1 more source
IMMUNOCYTOCHEMISTRY AND NEUROBIOLOGY
Quarterly Journal of Experimental Physiology, 1983 Immunocytochemistry enables the localization of transmitter‐related antigens in tissue sections at either the light microscopic or the electron microscopic level. In the case of neuropeptides and certain transmitters (e.g. serotonin) it has been possible to produce antibodies directed against the putative transmitter itself.
A.C. Cuello +2 more
openaire +3 more sources
Antibodies for immunolabeling by light and electron microscopy : not for the faint hearted [PDF]
, 2014 Reliable antibodies represent crucial tools in the arsenal of the cell biologist and using them to localize antigens for immunocytochemistry is one of their most important applications.
Griffiths, Gareth, Lucocq, John Milton
core +1 more source
Identification of a novel human E-Cadherin splice variant andassessment of its effects upon EMT-related events [PDF]
, 2018 Epithelial Cadherin (E-cadherin) is involved in calcium-dependent cell-cell adhesion and signal transduction. The E-cadherin decrease/loss is a hallmark of Epithelial to Mesenchymal Transition (EMT), a key event in tumor progression.
Besso, María José +8 more
core +1 more source
Frontiers in Systems Neuroscience, 2015 The medial prefrontal cortex (mPFC) exerts top-down control of primary visual cortex (V1) activity. As there is no direct neuronal projection from mPFC to V1, this functional connection may use an indirect route, i.e., via basalo-cortical cholinergic ...
Hoang Nam eNguyen +2 more
doaj +1 more source