Results 261 to 270 of about 171,680 (341)
LRRK2 interactions with microtubules are independent of LRRK2-mediated Rab phosphorylation. [PDF]
Malankhanova T +7 more
europepmc +1 more source
Mutations in GFAP Alter Early Lineage Commitment of Organoids
Main Points Mutations in GFAP alter lineage commitment of organoids. The severity of this commitment defect is dependent on method of embryoid body formation. GFAP is expressed in iPSCs and during early stages of organoid development. . ABSTRACT Glial fibrillary acidic protein (GFAP) is a type‐3 intermediate filament protein mainly expressed in ...
Werner Dykstra +14 more
wiley +1 more source
Immunocytochemical examination of Akt, mTOR, and Pax-2 for endometrial carcinoma through thin-layer endometrial cytology. [PDF]
Ma K +7 more
europepmc +1 more source
Hypothalamic Astrocytes Exhibit Glycolytic Features Making Them Prone for Glucose Sensing
Main Points Hypothalamic astrocytes versus cortical astrocytes: are more glycolytic due to high Pkm2, Glut1 and Mct4 expression do not exhibit glutamate‐induced glycolysis detect glucose concentration variations via an AMPK sensor with altered lactate production.
Sarah Geller +11 more
wiley +1 more source
Galectin-3 induces neurodevelopmental apical-basal polarity and regulates gyrification. [PDF]
Soares LC +16 more
europepmc +1 more source
Suppression of TRPV5 Regulates Microglia‐Mediated Neuroinflammation Following Status Epilepticus
Main Points TRPV5 is involved in microglial activation following epileptic seizures. TRPV5 upregulation in microglia drives neuroinflammation. TRPV5 inhibition by econazole reduces neuroinflammation via suppressing AKT/NF‐κB/NLRP3 signaling cascade. ABSTRACT Neuroinflammation, predominantly associated with glial activation and the release of various ...
Soojin Park +4 more
wiley +1 more source

