Results 271 to 280 of about 171,680 (341)

Primed human pluripotent stem cell-derived blastocyst-like cell aggregates with partial lineage specification. [PDF]

open access: yesRegen Ther
Mutsuda-Zapater K   +6 more
europepmc   +1 more source

Characterizing Piezoelectric‐Blended Polydimethylsiloxane for Use as a Mechanoelectrical Responsive Cell Culture Substrate

open access: yesJournal of Biomedical Materials Research Part A, Volume 113, Issue 11, November 2025.
ABSTRACT In this study, we developed a piezoelectric‐polydimethylsiloxane (pz‐PDMS) composite by blending poly(vinylidene fluoride‐co‐trifluoroethylene) (P(VDF‐TrFE)) with PDMS to create a biocompatible, mechanoelectrical responsive material. The pz‐PDMS was synthesized with varying piezoelectric concentrations (0%, 1%, 3%, and 5%) and characterized ...
Alexis P. Applequist   +3 more
wiley   +1 more source

Digoxin promotes anoikis of circulating cancer cells by targeting Na<sup>+</sup>/K<sup>+</sup>-ATPase α3-isoform. [PDF]

open access: yesCell Death Dis
Numata Y   +9 more
europepmc   +1 more source

Soft Scaffolds for Nerve Repair: Investigating Glycerol‐Plasticized Chitosan Microstructures With In Vitro Complex Models

open access: yesJournal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 113, Issue 11, November 2025.
ABSTRACT Peripheral nerve injuries are a significant clinical concern, often resulting in incomplete functional recovery due to the limitations of current treatments. Biomaterial‐based scaffolds that mimic the mechanical and topographical features of native nerve tissue represent a promising strategy to support regeneration.
Luca Scaccini   +11 more
wiley   +1 more source

CD40 in Clinical Inflammation: From Multiple Sclerosis to Atherosclerosis

open access: yesClinical and Developmental Immunology, 1998
Jon D. Laman   +2 more
doaj   +1 more source

Transforming Growth Factor‐β‐Mediated Fibrotic Remodeling Drives Chronic Kidney Disease in Methylmalonic Aciduria and Propionic Aciduria—Identification of a New Therapeutic Target

open access: yesJournal of Inherited Metabolic Disease, Volume 48, Issue 6, November 2025.
ABSTRACT Propionic aciduria (PA‐uria) and methylmalonic aciduria (MMA‐uria) are caused by defects in propionate catabolism. While chronic kidney disease (CKD) is a well‐established complication in MMA‐uria, renal involvement in PA‐uria has only come into focus more recently, and the underlying mechanisms remain poorly understood.
Karina A. Zeyer   +8 more
wiley   +1 more source

Treatment With Remdesivir Alone or in Combination With GS‐441524 in Cats With Ocular Involvement of Feline Infectious Peritonitis: An Observational Case Series

open access: yesJournal of Veterinary Internal Medicine, Volume 39, Issue 6, November/December 2025.
ABSTRACT Background Remdesivir and GS‐441524 have successfully treated cats with feline infectious peritonitis (FIP) but the changes in associated signs of ocular disease are not reported. Objective Evaluate the response of FIP‐associated signs of ocular disease before and after treatment with remdesivir, GS‐441524, or both.
Amy L. M. M. Andrews   +6 more
wiley   +1 more source

Alzheimer disease-associated tau post-translational modification mimics impact tau propagation and uptake. [PDF]

open access: yesJ Neuropathol Exp Neurol
Dickson JR   +9 more
europepmc   +1 more source

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