Results 141 to 150 of about 881,591 (335)

Specificity and Mechanism of Error-prone Replication by Human Immunodeficiency Virus-1 Reverse Transcriptase

, 1989
Katarzyna Bębenek, John Abbotts, John D. Roberts, Samuel H. Wilson, Thomas A. Kunkel   +4 more
openalex   +1 more source

AB1468 ENTEROPATHY IN DUTCH COMMON VARIABLE IMMUNODEFICIENCY COHORT [PDF]

, 2023
Norsham Juliana, Mirjam Severs, Jacques van Montfrans, Pauline M. Ellerbroek, Bas Oldenburg, J. Van Roon, Helen L. Leavis   +6 more
openalex   +1 more source

A Microbiota‐ and IL‐15‐Dependent Innate‐Like B Cell Progenitor Expressing E4BP4

Advanced Science, EarlyView.
This work identifies CD3.NKp46.CD19.NK1.1. NK‐B cells enriched in PDK1‐deficient yet present in wild‐type bone marrow. IL‐15 (via CD122) and TLR9‐microbiota signaling maintain their E4BP4 expression. These cells demonstrate innate immunity, preferentially differentiate into B cells, and unveil a novel microbiota‐ and IL‐15‐dependent regulatory pathway ...
Junming He, Xinlei Hou, Xiaomei Feng, Yayun Dong, Mengqi Ren, Surong Deng, Xinru Yang, Donglin Chen, Lingna Zhao, Shasha Chen, Meixiang Yang, Zhongjun Dong   +11 more
wiley   +1 more source

Reinfection results in accumulation of unintegrated viral DNA in cytopathic and persistent human immunodeficiency virus type 1 infection of CEM cells. [PDF]

, 1990
C. David Pauza, J Galindo, D. D. Richman
openalex   +1 more source

Brief Report of Anti–Programmed Cell Death Protein-1 in Human Immunodeficiency Virus Setting: Relevant and Breaking Results in First-Line NSCLC Therapy [PDF]

, 2021
Lise Bertin, Anthony Canellas, Baptiste Abbar, Marianne Veyri, Jean‐Philippe Spano, Jacques Cadranel, A. Lavolé   +6 more
openalex   +1 more source

Efferocytosis‐Driven Polyamine Metabolism in Macrophages Enhances Cancer Stem Cell Enrichment after Chemotherapy in Ovarian Cancer

Advanced Science, EarlyView.
Chemotherapy‐induced efferocytosis drives ovarian cancer stem cell enrichment. By engulfing apoptotic cancer cells, macrophages upregulate ODC1 and produce putrescine, which elevates osteopontin (OPN) expression. Secreted OPN then activates the CD44 receptor on cancer cells, promoting stemness and chemoresistance.
Wenhan Li, Feiquan Ying, Xinkai Pang, Qiulei Wu, Guoqing Li, Lin Huang, Jiayu Xin, Xiaoli Liu, Pan Liu, Xiaohan Xu, Shuran Tan, Yumei Gao, Tong Liu, Si Sun, Xiaoman Wang, Yiping Wen, Liqiong Cai, Shi Du, Yuan Zhang, Jing Cai   +19 more
wiley   +1 more source

Physicians Awareness on Primary Immunodeficiency Disorders in Iran

Iranian Journal of Allergy, Asthma and Immunology, 2012
Primary immunodeficiency diseases (PIDs) consist of a group of genetic disorders that predispose the patients to immune-mediated complications. The aim of this study was to assess the knowledge of Iranian general practitioners and pediatricians about ...
Keramat Nourijelyani, Asghar Aghamohammadi, Mohammad Salehi Sadaghiani, Nasrin Behniafard, Hassan Abolhassani, Sarvenaz Pourjabar, Alireza Rezvanizadeh, Joobin Khadamy, Amir Imanzaeh, Mojtaba Sedaghat, Nima Rezaei   +10 more
doaj  

A furin-defective cell line is able to process correctly the gp160 of human immunodeficiency virus type 1 [PDF]

, 1994
Yasuo Ohnishi, Tatsuo Shioda, Kazuhisa Nakayama, Shinya Iwata, Bin Gotoh, Michinari Hamaguchi, Yasuhiro Nagai   +6 more
openalex   +1 more source

PBRM1 Deficiency Reshapes an Immune Suppressive Microenvironment Through Epigenetic Tuning of PBRM1‐KDM5C‐IL6 Axis in ccRCC

Advanced Science, EarlyView.
PBRM1 ranks as the second most commonly mutated gene in ccRCC. This study reveals that PBRM1 loss promotes an immunosuppressive microenvironment by elevating M2 TAMs via the KDM5C–IL‐6 axis. These M2 TAMs, along with CAFs, form a barrier that excludes CD8+ T cells. Targeting IL‐6 synergizes with anti‐PD1 therapy, offering a promising strategy for PBRM1‐
Wenjiao Xia, Hongru Wang, Yu Dong, Zitong Yang, Yiyang Zhou, Zhinan Xia, Qinchen Li, Liangliang Ren, Yichun Zheng, Junliang Yan, Dongmei Ma, Zhi Chen, Xingang Cui, Guixin Zhu, Cheng Zhang   +14 more
wiley   +1 more source

Combined immunodeficiency disease associated with absence of cell-surface HLA-A and -B antigens

, 1978
Jean‐Louis Touraine, Hervé Betuel, Gérard Souillet, M Jeune   +3 more
openalex   +1 more source