Results 151 to 160 of about 863,721 (336)

STRUCTURE AND FUNCTION OF THE GASTROINTESTINAL TRACT IN PRIMARY IMMUNODEFICIENCY SYNDROMES A STUDY OF 39 PATIENTS

, 1973
Marvin E. Ament, Hans D. Ochs, Starkey D. Davis   +2 more
openalex   +1 more source

Chronic ER Stress Triggers Cell‐Surface Chaperones as the Therapeutic Targets of CAR Cells in Acute Myeloid Leukemia

Advanced Science, EarlyView.
Acute myeloid leukemia (AML) remains a therapeutic challenge due to its heterogeneity and limited targets. Here, multi‐omics analyses are utilized, and it is revealed that AML cells, particularly the FLT3‐ITD+ subtype, undergo chaperone‐mediated ER stress, inducing surface translocation of ER chaperones.
Yimin Zhou, Zhenfei Zhong, Peng Hu, Weigang Wang, Ying Song, Na Yang, Fangyan He, Yajie Li, Qi Sa, Yanmei Yang, Qinmiao Sun, Tonghua Yang, Beibei Zhang, Dahua Chen   +13 more
wiley   +1 more source

Serum IgD and IgE concentrations in immunodeficiency diseases.

, 1975
Rebecca H. Buckley, Susan A. Fiscus
openalex   +1 more source

709 ABNORMALITIES IN B CELL DIFFERENTIATION AND T CELL SUPPRESSION IN IMMUNODEFICIENCY WITH HYPER-IgM [PDF]

, 1978
Herbert J. Krantman, E. Richard Stiehm, Ronald H. Stevens, Andrew Saxon, W R C Seeger   +4 more
openalex   +1 more source

Accurate Generation of Conformational Ensembles for Intrinsically Disordered Proteins with IDPFold

Advanced Science, EarlyView.
In brief: IDPFold predicts the conformational ensembles of intrinsically disordered proteins (IDPs) from their amino acid sequences. The atomic structures generated by IDPFold offer crucial insights into the intricate relationship between IDP structures and their diverse biological functions.2 Abstract Intrinsically disordered proteins (IDPs) play ...
Junjie Zhu, Zhengxin Li, Zhuoqi Zheng, Bo Zhang, Bozitao Zhong, Jie Bai, Xiaokun Hong, Taifeng Wang, Ting Wei, Jianyi Yang, Hai‐Feng Chen   +10 more
wiley   +1 more source

Failure of lymphocyte-membrane HLA-A and -B expression in two siblings with combined immunodeficiency [PDF]

, 1979
Ruud K. B. Schuurman, J. J. van Rood, Jaak M. Vossen, P.Th.A. Schellekens, Th.M. Feltkamp-Vroom, E. Doyer, F.H.J. Gmelig-Meyling, H. K. A. Visser   +7 more
openalex   +1 more source

Red Blood Cell‐Derived Exosomal miR‐93‐5p Promotes Lung Cancer Progression through PTEN Suppression

Advanced Science, EarlyView.
Red blood cell (RBC)‐derived exosomal miR‐93‐5p is elevated in lung cancer patients and correlates with poor outcomes. Exosomal miR‐93‐5p suppresses PTEN in cancer cells, enhancing proliferation, migration, and invasion. In mouse models, therapeutic inhibition with ASO‐miR‐93 5p reduces tumor growth, highlighting a bidirectional tumor‐RBC‐tumor axis ...
Ning Li, Pushpa Dhilipkannah, Van K Holden, Ashutosh Sachdeva, Feng Jiang   +4 more
wiley   +1 more source

Corrigendum: Assessing the Functional Relevance of Variants in the IKAROS Family Zinc Finger Protein 1 (IKZF1) in a Cohort of Patients With Primary Immunodeficiency

Frontiers in Immunology, 2019
Zoya Eskandarian, Zoya Eskandarian, Manfred Fliegauf, Manfred Fliegauf, Alla Bulashevska, Michele Proietti, Rosie Hague, Cristian Roberto Smulski, Desirée Schubert, Klaus Warnatz, Bodo Grimbacher, Bodo Grimbacher, Bodo Grimbacher, Bodo Grimbacher, Bodo Grimbacher   +14 more
doaj   +1 more source

Phytohemagglutinin (PHA) skin test in the diagnosis of cellular immunodeficiency

, 1973
Glenn J. Lawlor, E. Richard Stiehm, Michael Kaplan, D.P.S. Sengar, Paul I. Terasaki   +4 more
openalex   +1 more source

Four families with immunodeficiency and chromosome abnormalities. [PDF]

, 1979
D. C. A. Candy, Anthony Hayward, D T Hughes, Lorna Layward, J F Soothill   +4 more
openalex   +1 more source